CHEK1
checkpoint kinase 1
别名:
CHK1
物种:
Human CHEK1 (1111), Mouse Chek1 (12649), Rat Chek1 (140583), naked mole-rat Chek1 (101701035), sheep CHEK1 (101111403), domestic guinea pig Chek1 (100719613), Zebrafish chek1 (393162), domestic cat CHEK1 (101083365), dog CHEK1 (609767), Horse CHEK1 (100064353)
UniProtKB ID:
基因ID:
- Human(1111) Summary: The protein encoded by this gene belongs to the Ser/Thr protein kinase family. It is required for checkpoint mediated cell cycle arrest in response to DNA damage or the presence of unreplicated DNA. This protein acts to integrate signals from ATM and ATR, two cell cycle proteins involved in DNA damage responses, that also associate with chromatin in meiotic prophase I. Phosphorylation of CDC25A protein phosphatase by this protein is required for cells to delay cell cycle progression in response to double-strand DNA breaks. Several alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Oct 2011]
- Mouse(12649) checkpoint kinase 1
- Rat(140583) checkpoint kinase 1
- naked mole-rat(101701035) checkpoint kinase 1
- sheep(101111403) checkpoint kinase 1
- domestic guinea pig(100719613) checkpoint kinase 1
- Zebrafish(393162) CHK1 checkpoint homolog (S. pombe)
- domestic cat(101083365) checkpoint kinase 1
- dog(609767) checkpoint kinase 1
- Horse(100064353) checkpoint kinase 1
- cow(513678) CHK1 checkpoint homolog (S. pombe)
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Antibodies
产品编号
说明
物种反应性
应用
PhosphoDetect Anti-Chk1 (pSer³¹⁷) Rabbit pAb, liquid, Calbiochem®,
物种反应性
human, monkey, mouse, rat
应用
Proteins
Small Molecule - Substrate
产品编号
说明
物种
CHKtide (CHK1/CHK2 substrate peptide), CHKtide (CHK1/CHK2 substrate peptide) primarily used in Kinase Assays.,
物种
human