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Merck

OLIGO

定制DNA寡核苷酸

Design and Order Custom Oligos

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DNA引物, ISO 13485寡核苷酸, NGS 适配体, NGS−级寡核苷酸, cGMP寡核苷酸, 二−代测序寡核苷酸, 二−代测序适配体, 修饰寡核苷酸, 定制DNA寡核苷酸, 寡核苷酸, 板中的寡核苷酸, 脱氧核糖核酸, 锁核酸寡核苷酸, 高通量 DNA

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41105327

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Fuqiang Chen et al.
Nature methods, 8(9), 753-755 (2011-07-19)
Zinc-finger nucleases (ZFNs) have enabled highly efficient gene targeting in multiple cell types and organisms. Here we describe methods for using simple ssDNA oligonucleotides in tandem with ZFNs to efficiently produce human cell lines with three distinct genetic outcomes: (i)
T N Wiegner et al.
Marine pollution bulletin, 114(2), 952-961 (2016-11-22)
Spatial and temporal patterns of coastal microbial pollution are not well documented. Our study examined these patterns through measurements of fecal indicator bacteria (FIB), nutrients, and physiochemical parameters in Hilo Bay, Hawai'i, during high and low river flow. >40% of
Eun Jung Thak et al.
Journal of microbiology (Seoul, Korea), 56(1), 11-23 (2018-01-05)
Protein glycosylation, the most universal and diverse post-translational modification, can affect protein secretion, stability, and immunogenicity. The structures of glycans attached to proteins are quite diverse among different organisms and even within yeast species. In yeast, protein glycosylation plays key
Leonel Armas-López et al.
Oncotarget, 8(40), 67056-67081 (2017-10-06)
Several homeobox-related gene (HOX) transcription factors such as mesenchyme HOX-2 (MEOX2) have previously been associated with cancer drug resistance, malignant progression and/or clinical prognostic responses in lung cancer patients; however, the mechanisms involved in these responses have yet to be
Hyong Woo Choi et al.
PloS one, 10(11), e0143447-e0143447 (2015-11-26)
The plant hormone salicylic acid (SA) controls several physiological processes and is a key regulator of multiple levels of plant immunity. To decipher the mechanisms through which SA's multiple physiological effects are mediated, particularly in immunity, two high-throughput screens were
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商品

Custom Oligos Modifications

We offer over 200 custom DNA oligos modification for both DNA, RNA oligonucleotides and sequencing to probes for gene.

Dual-Labeled Probes

Dual-Labeled Probes are the most common probe type for qPCR and are often referred to as hydrolysis probes.

Molecular Beacons

Learn about precision Sigma-Aldrich Molecular Beacon oligonucleotide probes used for sequence detection in qPCR for in vitro research.

Oligonucleotide Purification

Learn about the importance of oligonucleotide purification, recommended methods, common techniques and applications, and key steps in the processes.

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相关内容

单克隆抗体生产和纯化

技术方面的重大进展让单克隆抗体生产更快速高效。现有三个成熟的抗体发现平台。我们提供基于不同技术生产单克隆抗体所需的试剂。

LightCycler® Probes

LightCycler probes are highly sensitive and sequence-specific fluorescent probes designed for use with the Roche LightCycler instruments.

No Template Control Oligos (NTCO)

If laboratory handling error has been ruled out, contaminated primers and probes may be to blame for a signal from the qPCR no template control.

Oligonucleotide QA: Quality Management System

QMS features certificates, document control, vendor management, and corrective actions, ensuring quality management standards.

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