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Merck

FGG

fibrinogen gamma chain

Synonymes:
Espèce(s):
ID UniProtKB:
ID du gène:
  • Human(2266) Summary: The protein encoded by this gene is the gamma component of fibrinogen, a blood-borne glycoprotein comprised of three pairs of nonidentical polypeptide chains. Following vascular injury, fibrinogen is cleaved by thrombin to form fibrin which is the most abundant component of blood clots. In addition, various cleavage products of fibrinogen and fibrin regulate cell adhesion and spreading, display vasoconstrictor and chemotactic activities, and are mitogens for several cell types. Mutations in this gene lead to several disorders, including dysfibrinogenemia, hypofibrinogenemia and thrombophilia. Alternative splicing results in two transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008]
  • Mouse(99571) fibrinogen gamma chain
  • Rat(24367) fibrinogen gamma chain
  • Zebrafish(406327) fibrinogen, gamma polypeptide
  • chicken(395837) fibrinogen gamma chain
  • domestic cat(101092680) fibrinogen gamma chain
  • dog(475474) fibrinogen gamma chain
  • cow(280792) fibrinogen gamma chain
  • Horse(100147221) fibrinogen gamma chain
  • Domestic Rabbit(100351591) fibrinogen gamma chain
  • naked mole-rat(101696987) fibrinogen gamma chain
  • domestic guinea pig(100720373) fibrinogen gamma chain

Custom & Knockdown Gene Products

Antibodies

Numéro du produit
Description
Espèces réactives
Application
Anti-FGG antibody produced in rabbit, IgG fraction of antiserum,
Espèces réactives
dog, guinea pig, human, mouse, rabbit, rat
Application
western blot
Anti-FGG antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Espèces réactives
human
Application
immunohistochemistry
Anti-FGG antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Espèces réactives
human
Application
immunofluorescence
western blot
Anti-Fibrinogen antibody produced in goat, whole antiserum,
Espèces réactives
human
Application
ELISA
quantitative precipitin assay
Monoclonal Anti-Fibrinogen antibody produced in mouse, clone 85D4, ascites fluid,
Espèces réactives
baboon, bovine, canine, goat, human, pig, rabbit, sheep
Application
ELISA
dot blot

western blot

Proteins

Numéro du produit
Description
Espèce(s)
Fibrinogène from bovine plasma, Type I-S, 65-85% protein (≥75% of protein is clottable),
Espèce(s)
cow
Fibrinogène from human plasma, 50-70% protein (≥80% of protein is clottable),
Espèce(s)
human
Fibrinogène from human plasma, 35-65% protein (≥90% of protein is clottable).,
Espèce(s)
human
Fibrin from human plasma, insoluble powder,
Espèce(s)
human
Fibrinogen from rat plasma, 60-80% protein (≥60% of protein is clottable),
Espèce(s)
rat

esiRNA

Numéro du produit
Description
Espèce(s)
MISSION® esiRNA, targeting human FGG,
Espèce(s)
human
MISSION® esiRNA, targeting mouse Fgg,
Espèce(s)
mouse