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GCDH

glutaryl-CoA dehydrogenase

Sinónimos:
ACAD5, GCD
Especie:
ID UniProtKB:
ID del gen:
  • Human(2639) Summary: The protein encoded by this gene belongs to the acyl-CoA dehydrogenase family. It catalyzes the oxidative decarboxylation of glutaryl-CoA to crotonyl-CoA and CO(2) in the degradative pathway of L-lysine, L-hydroxylysine, and L-tryptophan metabolism. It uses electron transfer flavoprotein as its electron acceptor. The enzyme exists in the mitochondrial matrix as a homotetramer of 45-kD subunits. Mutations in this gene result in the metabolic disorder glutaric aciduria type 1, which is also known as glutaric acidemia type I. Alternative splicing of this gene results in multiple transcript variants. A related pseudogene has been identified on chromosome 12. [provided by RefSeq, Mar 2013]
  • Mouse(270076) glutaryl-Coenzyme A dehydrogenase
  • Rat(364975) glutaryl-CoA dehydrogenase
  • Zebrafish(393860) glutaryl-Coenzyme A dehydrogenase
  • sheep(101122190) glutaryl-CoA dehydrogenase
  • chicken(771098) glutaryl-CoA dehydrogenase
  • domestic cat(101086880) glutaryl-CoA dehydrogenase
  • dog(476696) glutaryl-CoA dehydrogenase
  • domestic guinea pig(100714939) glutaryl-CoA dehydrogenase
  • cow(506310) glutaryl-CoA dehydrogenase
  • Horse(100063310) glutaryl-CoA dehydrogenase
  • Domestic Rabbit(100343376) glutaryl-CoA dehydrogenase
  • naked mole-rat(101718348) glutaryl-CoA dehydrogenase

Custom & Knockdown Gene Products

Antibodies

Número de producto
Descripción
Reactividad de especies
Aplicación
Anti-GCDH antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Reactividad de especies
human
Aplicación
immunohistochemistry
western blot
Anti-GCDH antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Reactividad de especies
human
Aplicación
immunofluorescence
immunohistochemistry

western blot
Anti-GCDH antibody produced in rabbit, IgG fraction of antiserum,
Reactividad de especies
dog, horse, human, mouse, pig, rabbit, rat
Aplicación
immunohistochemistry
western blot

esiRNA

Número de producto
Descripción
Especie
MISSION® esiRNA, targeting human GCDH,
Especie
human
MISSION® esiRNA, targeting mouse Gcdh,
Especie
mouse