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Merck

SIGMAR1

sigma non-opioid intracellular receptor 1

Synonyms:
ALS16, OPRS1, SIG-1R, SR-BP, SR-BP1, SRBP, hSigmaR1, sigma1R
Species:
UniProtKB ID:
Gene ID:
  • Human(10280) Summary: This gene encodes a receptor protein that interacts with a variety of psychotomimetic drugs, including cocaine and amphetamines. The receptor is believed to play an important role in the cellular functions of various tissues associated with the endocrine, immune, and nervous systems. As indicated by its previous name, opioid receptor sigma 1 (OPRS1), the product of this gene was erroneously thought to function as an opioid receptor; it is now thought to be a non-opioid receptor. Alternative splicing of this gene results in transcript variants encoding distinct isoforms. [provided by RefSeq, Dec 2008]
  • Mouse(18391) sigma non-opioid intracellular receptor 1
  • Rat(29336) sigma non-opioid intracellular receptor 1
  • domestic guinea pig(100135589) sigma non-opioid intracellular receptor 1
  • cow(538903) sigma non-opioid intracellular receptor 1
  • sheep(101116710) sigma non-opioid intracellular receptor 1
  • domestic cat(101084912) sigma non-opioid intracellular receptor 1
  • Zebrafish(393952) sigma non-opioid intracellular receptor 1
  • chicken(100859748) sigma non-opioid intracellular receptor 1
  • dog(481587) sigma non-opioid intracellular receptor 1
  • naked mole-rat(101707150) sigma non-opioid intracellular receptor 1

Custom & Knockdown Gene Products

Small Molecule - Agonist

Product Number
Description
Species
Dextromethorphan HBr, certified reference material, pharmaceutical secondary standard,
Species
human
Dextromethorphan hydrobromide, meets USP testing specifications,
Species
human
Dextromethorphan hydrobromide, United States Pharmacopeia (USP) Reference Standard,
Species
human
Dextromethorphan solution, 1.0 mg/mL in methanol, ampule of 1 mL, certified reference material, Cerilliant®,
Species
human
Dextromethorphan hydrobromide, European Pharmacopoeia (EP) Reference Standard,
Species
human