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Merck

ANTXR1

anthrax toxin receptor 1

Sinônimos:
ATR, GAPO, TEM8
Espécies:
ID UniProtKB:
ID do gene:
  • Human(84168) Summary: This gene encodes a type I transmembrane protein and is a tumor-specific endothelial marker that has been implicated in colorectal cancer. The encoded protein has been shown to also be a docking protein or receptor for Bacillus anthracis toxin, the causative agent of the disease, anthrax. The binding of the protective antigen (PA) component, of the tripartite anthrax toxin, to this receptor protein mediates delivery of toxin components to the cytosol of cells. Once inside the cell, the other two components of anthrax toxin, edema factor (EF) and lethal factor (LF) disrupt normal cellular processes. Three alternatively spliced variants that encode different protein isoforms have been described. [provided by RefSeq, Oct 2008]
  • Mouse(69538) anthrax toxin receptor 1
  • Rat(362393) anthrax toxin receptor 1
  • naked mole-rat(101701494) anthrax toxin receptor 1
  • domestic guinea pig(100728514) anthrax toxin receptor 1
  • sheep(101108204) anthrax toxin receptor 1
  • Domestic Rabbit(100357637) anthrax toxin receptor 1
  • cow(616010) anthrax toxin receptor 1
  • domestic cat(101092930) anthrax toxin receptor 1
  • Horse(100061334) anthrax toxin receptor 1
  • dog(612601) anthrax toxin receptor 1
  • chicken(428199) anthrax toxin receptor 1

Custom & Knockdown Gene Products

Antibodies

Número do produto
Descrição
Reatividade de espécies
Aplicação
Anti-ATR antibody produced in rabbit, purified antibody (Ion exchange),
Reatividade de espécies
Aplicação
immunofluorescence
immunohistochemistry

western blot
Anti-ATR antibody produced in rabbit, purified antibody (Ion exchange),
Reatividade de espécies
Aplicação
immunofluorescence
western blot
Anti-ANTXR1 antibody produced in rabbit, affinity isolated antibody,
Reatividade de espécies
bovine, dog, guinea pig, horse, human, mouse, rabbit, rat
Aplicação
western blot

esiRNA

Número do produto
Descrição
Espécies
MISSION® esiRNA, targeting human ANTXR1,
Espécies
human
MISSION® esiRNA, targeting mouse Antxr1,
Espécies
mouse