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Merck

BCKDHA

branched chain keto acid dehydrogenase E1, alpha polypeptide

Sinónimos:
BCKDE1A, MSU, MSUD1, OVD1A
Especie:
ID UniProtKB:
ID del gen:
  • Human(593) Summary: The branched-chain alpha-keto acid (BCAA) dehydrogenase (BCKD) complex is an innter mitochondrial enzyme complex that catalyzes the second major step in the catabolism of the branched-chain amino acids leucine, isoleucine, and valine. The BCKD complex consists of three catalytic components: a heterotetrameric (alpha2-beta2) branched-chain alpha-keto acid decarboxylase (E1), a dihydrolipoyl transacylase (E2), and a dihydrolipoamide dehydrogenase (E3). This gene encodes the alpha subunit of the decarboxylase (E1) component. Mutations in this gene result in maple syrup urine disease, type IA. Multiple transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Sep 2009]
  • Mouse(12039) branched chain ketoacid dehydrogenase E1, alpha polypeptide
  • Rat(25244) branched chain ketoacid dehydrogenase E1, alpha polypeptide
  • Horse(100068678) branched chain keto acid dehydrogenase E1, alpha polypeptide
  • chicken(374210) branched chain keto acid dehydrogenase E1, alpha polypeptide
  • cow(282149) branched chain keto acid dehydrogenase E1, alpha polypeptide
  • sheep(100145857) branched chain keto acid dehydrogenase E1, alpha polypeptide
  • Zebrafish(554124) branched chain keto acid dehydrogenase E1, alpha polypeptide
  • domestic cat(101087186) branched chain keto acid dehydrogenase E1, alpha polypeptide
  • domestic guinea pig(100715185) branched chain keto acid dehydrogenase E1, alpha polypeptide
  • naked mole-rat(101705928) branched chain keto acid dehydrogenase E1, alpha polypeptide
  • Domestic Rabbit(100352048) branched chain keto acid dehydrogenase E1, alpha polypeptide
  • dog(484488) branched chain keto acid dehydrogenase E1, alpha polypeptide

Custom & Knockdown Gene Products

esiRNA

Número de producto
Descripción
Especie
MISSION® esiRNA, targeting human BCKDHA, CTC-435M10.3,
Especie
human