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CACNA2D1

calcium channel, voltage-dependent, alpha 2/delta subunit 1

Synonimy:
CACNA2, CACNL2A, CCHL2A
Gatunek:
Identyfikator UniProtKB:
Identyfikator genu:
  • Human(781) Summary: This gene encodes a member of the alpha-2/delta subunit family, a protein in the voltage-dependent calcium channel complex. Calcium channels mediate the influx of calcium ions into the cell upon membrane polarization and consist of a complex of alpha-1, alpha-2/delta, beta, and gamma subunits in a 1:1:1:1 ratio. Research on a highly similar protein in rabbit suggests the protein described in this record is cleaved into alpha-2 and delta subunits. Alternate transcriptional splice variants of this gene have been observed but have not been thoroughly characterized. [provided by RefSeq, Jul 2008]
  • Mouse(12293) calcium channel, voltage-dependent, alpha2/delta subunit 1
  • Rat(25399) calcium channel, voltage-dependent, alpha2/delta subunit 1
  • chicken(768444) calcium channel, voltage-dependent, alpha 2/delta subunit 1
  • domestic guinea pig(100728887) calcium channel, voltage-dependent, alpha 2/delta subunit 1
  • naked mole-rat(101708369) calcium channel, voltage-dependent, alpha 2/delta subunit 1
  • cow(282608) calcium channel, voltage-dependent, alpha 2/delta subunit 1
  • sheep(101123550) calcium channel, voltage-dependent, alpha 2/delta subunit 1
  • dog(610342) calcium channel, voltage-dependent, alpha 2/delta subunit 1
  • Domestic Rabbit(100009105) calcium channel, voltage-dependent, alpha 2/delta subunit 1
  • domestic cat(101099450) calcium channel, voltage-dependent, alpha 2/delta subunit 1

Custom & Knockdown Gene Products

Small Molecule - Allosteric Modulator

Numer produktu
Opis
Gatunek
Gabapentin solution, 1.0 mg/mL in methanol, ampule of 1 mL, certified reference material, Cerilliant®,
Gatunek
human
Gabapentin, Pharmaceutical Secondary Standard; Certified Reference Material,
Gatunek
human
Gabapentin, United States Pharmacopeia (USP) Reference Standard,
Gatunek
human
Gabapentin, European Pharmacopoeia (EP) Reference Standard,
Gatunek
human
Pregabalin, European Pharmacopoeia (EP) Reference Standard,
Gatunek
human

Small Molecule - Antagonist

Numer produktu
Opis
Gatunek
Felodipine, solid,
Gatunek
human
Nifedipine, ≥98% (HPLC), powder,
Gatunek
rat, mouse, human
Gabapentin, solid,
Gatunek
human, rat
Terodiline hydrochloride, ≥98% (HPLC), solid,
Gatunek
human

Antibodies

Numer produktu
Opis
Reaktywność gatunkowa
Zastosowanie
Anti-CACNA2D1 antibody produced in rabbit, affinity isolated antibody, buffered aqueous glycerol solution,
Reaktywność gatunkowa
human
Zastosowanie
immunohistochemistry
Anti-CACNA2D1 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Reaktywność gatunkowa
human
Zastosowanie
immunohistochemistry
Anti-CACNA2D1 antibody produced in goat, affinity isolated antibody, buffered aqueous solution,
Reaktywność gatunkowa
human
Zastosowanie
ELISA
western blot
Anti-Calcium Channel Antibody, Voltage Gated α 2/δ-1, L-type, Chemicon®, from rabbit,
Reaktywność gatunkowa
rat
Zastosowanie
western blot
Anti-CACNA2D1 antibody produced in rabbit, affinity isolated antibody,
Reaktywność gatunkowa
bovine, dog, guinea pig, horse, human, mouse, rabbit, rat
Zastosowanie
western blot

Small Molecule - Blocker

Numer produktu
Opis
Gatunek
Isradipine, ≥98% (HPLC), solid,
Gatunek
human
Felodipine, solid,
Gatunek
human
Nifedipine, ≥98% (HPLC), powder,
Gatunek
rat, mouse, human
Bepridil hydrochloride, powder,
Gatunek
human
Terodiline hydrochloride, ≥98% (HPLC), solid,
Gatunek
human

esiRNA

Numer produktu
Opis
Gatunek
MISSION® esiRNA, targeting mouse Cacna2d1,
Gatunek
mouse
MISSION® esiRNA, targeting human CACNA2D1,
Gatunek
human
MISSION® esiRNA, targeting mouse Cacna2d1,
Gatunek
mouse