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CD86

CD86 molecule

Synonyms:
B7-2, B7.2, B70, CD28LG2, LAB72
Species:
UniProtKB ID:
Gene ID:
  • Human(942) Summary: This gene encodes a type I membrane protein that is a member of the immunoglobulin superfamily. This protein is expressed by antigen-presenting cells, and it is the ligand for two proteins at the cell surface of T cells, CD28 antigen and cytotoxic T-lymphocyte-associated protein 4. Binding of this protein with CD28 antigen is a costimulatory signal for activation of the T-cell. Binding of this protein with cytotoxic T-lymphocyte-associated protein 4 negatively regulates T-cell activation and diminishes the immune response. Alternative splicing results in several transcript variants encoding different isoforms.[provided by RefSeq, May 2011]
  • Mouse(12524) CD86 antigen
  • Rat(56822) CD86 molecule
  • domestic guinea pig(101787434) CD86 molecule
  • naked mole-rat(101724342) CD86 molecule
  • chicken(427944) CD86 molecule
  • dog(403764) CD86 molecule
  • domestic cat(493704) CD86 molecule
  • cow(414345) CD86 molecule
  • Domestic Rabbit(100008999) CD86 molecule

Custom & Knockdown Gene Products

ELISA

Product Number
Description
Species
Rat CD86 / CD86 Antigen, Isoform CRA-c ELISA Kit, ,
Species
rat
Human CD86/B7-2 ELISA Kit, for cell culture supernatants, plasma, and serum samples,
Species
human

Antibodies

Product Number
Description
Species Reactivity
Application
Anti-CD86 antibody produced in rabbit, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human
Application
proximity ligation assay
western blot
Anti-CD86 antibody produced in rabbit, ,
Species Reactivity
human, mouse, rat
Application
immunofluorescence
immunohistochemistry

western blot
Anti-CD86 antibody produced in rabbit, ,
Species Reactivity
human
Application
immunohistochemistry
western blot
Anti-CD86 (B7-2) Antibody (human), PE, clone IT2.2, clone IT2.2, from mouse,
Species Reactivity
human
Application
flow cytometry
immunohistochemistry

immunoprecipitation (IP)
Anti-CD86 (B7-2) Antibody (mouse), PE, clone GL-1, clone GL-1 (GL1), 0.2 mg/mL, from rat,
Species Reactivity
mouse
Application
flow cytometry
immunofluorescence

immunohistochemistry

esiRNA

Product Number
Description
Species
MISSION® esiRNA, targeting human CD86,
Species
human