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Merck

CYP19A1

cytochrome P450, family 19, subfamily A, polypeptide 1

Sinónimos:
ARO, ARO1, CPV1, CYAR, CYP19, CYPXIX, P-450AROM
Especie:
Human CYP19A1 (1588), Mouse Cyp19a1 (13075), Rat Cyp19a1 (25147), Goat CYP19A1 (100861413), Horse CYP19A1 (100009712), dog CYP19A1 (494003), chicken CYP19A1 (414854), Domestic Rabbit CYP19A1 (100328545), cow CYP19A1 (281740)
ID UniProtKB:
P11511, Q16731, Q3B764, Q58FA0
ID del gen:
  • Human(1588) Summary: This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum and catalyzes the last steps of estrogen biosynthesis, three successive hydroxylations of the A ring of androgens. Mutations in this gene can result in either increased or decreased aromatase activity; the associated phenotypes suggest that estrogen functions both as a sex steroid hormone and in growth or differentiation. The gene expresses two transcript variants. [provided by RefSeq, Jul 2008]
  • Mouse(13075) cytochrome P450, family 19, subfamily a, polypeptide 1
  • Rat(25147) cytochrome P450, family 19, subfamily a, polypeptide 1
  • Goat(100861413) cytochrome P450, family 19, subfamily A, polypeptide 1
  • Horse(100009712) cytochrome P450, family 19, subfamily A, polypeptide 1
  • dog(494003) cytochrome P450, family 17, subfamily A, polypeptide 1
  • chicken(414854) cytochrome P450, family 19, subfamily A, polypeptide 1
  • Domestic Rabbit(100328545) cytochrome P450, family 19, subfamily A, polypeptide 1
  • cow(281740) cytochrome P450, family 19, subfamily A, polypeptide 1

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Antibodies

Número de producto
Descripción
Reactividad de especies
Aplicación
HPA051194
Anti-CYP19A1 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Reactividad de especies
human
Aplicación
immunofluorescence
immunohistochemistry
ZRB2945
Anti-Aromatase Antibody, clone 1D23 ZooMAb® Rabbit Monoclonal, recombinant, expressed in HEK 293 cells,
Reactividad de especies
human, monkey
Aplicación
affinity binding assay
immunohistochemistry
western blot
SAB5702040
Anti-Aromatase (CYP19A1) Antibody, clone 5C5N7, Rabbit Monoclonal, ,
Reactividad de especies
human
Aplicación
immunofluorescence
immunohistochemistry
western blot
SAB4500606
Anti-Cytochrome P450 19A1 antibody produced in rabbit, affinity isolated antibody,
Reactividad de especies
human, mouse, rat
Aplicación
ELISA
immunofluorescence
immunohistochemistry
western blot
SAB1410280
Anti-CYP19A1 antibody produced in rabbit, purified immunoglobulin, buffered aqueous solution,
Reactividad de especies
human
Aplicación
western blot

Cell Lines

Número de producto
Descripción
Especie
MTOXCE19A1
CypExpress™ Aromatase, ,
Especie
human

Small Molecule - Inhibitor

Número de producto
Descripción
Especie
L6545
Letrozole, ≥98% (HPLC),
Especie
human
PHR1540
Letrozole, Pharmaceutical Secondary Standard; Certified Reference Material,
Especie
human
1356971
Letrozole, United States Pharmacopeia (USP) Reference Standard,
Especie
human
PZ0006
Exemestane, ≥98% (HPLC),
Especie
human
F2552
Formestane, solid,
Especie
human

Small Molecule - Ligand

Número de producto
Descripción
Especie
A9657
DL-Aminoglutethimide, ,
Especie
human, rat

esiRNA

Número de producto
Descripción
Especie
EHU036781
MISSION® esiRNA, targeting human CYP19A1,
Especie
human
EMU044241
MISSION® esiRNA, targeting mouse Cyp19a1,
Especie
mouse