CYP8B1
cytochrome P450, family 8, subfamily B, polypeptide 1
Sinónimos:
CP8B, CYP12
Especie:
Human CYP8B1 (1582), Mouse Cyp8b1 (13124), Rat Cyp8b1 (81924), Zebrafish cyp8b1 (445281), cow CYP8B1 (538964), chicken CYP8B1 (425055), Domestic Rabbit CYP8B1 (100009301)
ID UniProtKB:
ID del gen:
- Human(1582) Summary: This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This endoplasmic reticulum membrane protein catalyzes the conversion of 7 alpha-hydroxy-4-cholesten-3-one into 7-alpha,12-alpha-dihydroxy-4-cholesten-3-one. The balance between these two steroids determines the relative amounts of cholic acid and chenodeoxycholic acid both of which are secreted in the bile and affect the solubility of cholesterol. This gene is unique among the cytochrome P450 genes in that it is intronless. [provided by RefSeq, Jul 2008]
- Mouse(13124) cytochrome P450, family 8, subfamily b, polypeptide 1
- Rat(81924) cytochrome P450, family 8, subfamily b, polypeptide 1
- Zebrafish(445281) cytochrome P450, family 8, subfamily B, polypeptide 1
- cow(538964) cytochrome P450, family 8, subfamily B, polypeptide 1
- chicken(425055) cytochrome P450, family 8, subfamily B, polypeptide 1
- Domestic Rabbit(100009301) cytochrome P450, family 8, subfamily B, polypeptide 1
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