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Merck

DHCR24

24-dehydrocholesterol reductase

Synonimy:
DCE, Nbla03646, SELADIN1, seladin-1
Gatunek:
Identyfikator UniProtKB:
Identyfikator genu:
  • Human(1718) Summary: This gene encodes a flavin adenine dinucleotide (FAD)-dependent oxidoreductase which catalyzes the reduction of the delta-24 double bond of sterol intermediates during cholesterol biosynthesis. The protein contains a leader sequence that directs it to the endoplasmic reticulum membrane. Missense mutations in this gene have been associated with desmosterolosis. Also, reduced expression of the gene occurs in the temporal cortex of Alzheimer disease patients and overexpression has been observed in adrenal gland cancer cells. [provided by RefSeq, Jul 2008]
  • Mouse(74754) 24-dehydrocholesterol reductase
  • Rat(298298) 24-dehydrocholesterol reductase
  • domestic guinea pig(100714000) 24-dehydrocholesterol reductase
  • naked mole-rat(101703975) 24-dehydrocholesterol reductase
  • dog(489573) 24-dehydrocholesterol reductase
  • domestic cat(101098730) 24-dehydrocholesterol reductase
  • Horse(100034055) 24-dehydrocholesterol reductase
  • cow(533726) 24-dehydrocholesterol reductase
  • sheep(101123162) 24-dehydrocholesterol reductase
  • Zebrafish(494102) 24-dehydrocholesterol reductase
  • chicken(424661) 24-dehydrocholesterol reductase

Custom & Knockdown Gene Products

Antibodies

Numer produktu
Opis
Reaktywność gatunkowa
Zastosowanie
Anti-DHCR24 antibody produced in rabbit, affinity isolated antibody,
Reaktywność gatunkowa
bovine, human, mouse, rabbit, rat
Zastosowanie
western blot
Anti-DHCR24 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody,
Reaktywność gatunkowa
human
Zastosowanie
immunohistochemistry
Anti-DHCR24 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Reaktywność gatunkowa
human
Zastosowanie
immunohistochemistry
western blot

Small Molecule - Inhibitor

Numer produktu
Opis
Gatunek
Triparanol, ≥97% (HPLC), powder,
Gatunek
human

esiRNA

Numer produktu
Opis
Gatunek
MISSION® esiRNA, targeting human DHCR24,
Gatunek
human
MISSION® esiRNA, targeting mouse Dhcr24,
Gatunek
mouse