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Merck

FMR1

fragile X mental retardation 1

Sinonimi:
FMRP, FRAXA, POF, POF1
Specie:
Human FMR1 (2332), Mouse Fmr1 (14265), Rat Fmr1 (24948), naked mole-rat Fmr1 (101707722), Zebrafish fmr1 (259191), sheep FMR1 (101117478), domestic guinea pig Fmr1 (100734782), chicken FMR1 (422395), fruit fly Fmr1 (37528), cow FMR1 (507482) ...Più
ID UniProtKB:
Q06787, A6NNH4, D3DWT0, D3DWT1, D3DWT2, Q16578, Q5PQZ6, Q99054
ID gene:
  • Human(2332) Summary: The protein encoded by this gene binds RNA and is associated with polysomes. The encoded protein may be involved in mRNA trafficking from the nucleus to the cytoplasm. A trinucleotide repeat (CGG) in the 5' UTR is normally found at 6-53 copies, but an expansion to 55-230 repeats is the cause of fragile X syndrome. Expansion of the trinucleotide repeat may also cause one form of premature ovarian failure (POF1). Multiple alternatively spliced transcript variants that encode different protein isoforms and which are located in different cellular locations have been described for this gene. [provided by RefSeq, May 2010]
  • Mouse(14265) fragile X mental retardation syndrome 1
  • Rat(24948) fragile X mental retardation 1
  • naked mole-rat(101707722) fragile X mental retardation 1
  • Zebrafish(259191) fragile X mental retardation 1
  • sheep(101117478) fragile X mental retardation 1
  • domestic guinea pig(100734782) fragile X mental retardation 1
  • chicken(422395) fragile X mental retardation 1
  • fruit fly(37528) CG6203 gene product from transcript CG6203-RC
  • cow(507482) fragile X mental retardation 1
  • domestic cat(101080266) fragile X mental retardation 1
  • dog(481070) fragile X mental retardation 1

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Antibodies

Numero di prodotto
Descrizione
Reattività con
Applicazione
MABN2280
Anti-FMR1polyG Antibody, clone 8FM-2F7, ascites fluid, clone 8FM-2F7, from mouse,
Reattività con
human
Applicazione
immunofluorescence
immunohistochemistry
western blot
SAB1403834
Monoclonal Anti-FMR1 antibody produced in mouse, clone 3E11, purified immunoglobulin, buffered aqueous solution,
Reattività con
human
Applicazione
ELISA
western blot
HPA050118
Anti-FMR1 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Reattività con
human
Applicazione
immunofluorescence
immunohistochemistry
HPA056084
Anti-FMR1 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Reattività con
human
Applicazione
immunohistochemistry
SAB5702978
Anti-FMRP Antibody, clone 4Y8I5, Rabbit Monoclonal, ,
Reattività con
human, rat
Applicazione
immunohistochemistry
immunoprecipitation (IP)
western blot

esiRNA

Numero di prodotto
Descrizione
Specie
EHU082131
MISSION® esiRNA, targeting human FMR1,
Specie
human
EMU039161
MISSION® esiRNA, targeting mouse Fmr1,
Specie
mouse
EHU222651
MISSION® esiRNA, targeting human FMR1-AS1,
Specie
human