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Merck

GLRB

glycine receptor, beta

Sinonimi:
HKPX2
Specie:
ID UniProtKB:
ID gene:
  • Human(2743) Summary: This gene encodes the beta subunit of the glycine receptor, which is a pentamer composed of alpha and beta subunits. The receptor functions as a neurotransmitter-gated ion channel, which produces hyperpolarization via increased chloride conductance due to the binding of glycine to the receptor. Mutations in this gene cause startle disease, also known as hereditary hyperekplexia or congenital stiff-person syndrome, a disease characterized by muscular rigidity. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2009]
  • Mouse(14658) glycine receptor, beta subunit
  • Rat(25456) glycine receptor, beta
  • naked mole-rat(101709956) glycine receptor, beta
  • dog(475477) glycine receptor, beta
  • Horse(100061981) glycine receptor, beta
  • domestic cat(101088482) glycine receptor, beta
  • cow(281198) glycine receptor, beta
  • sheep(101109484) glycine receptor, beta
  • domestic guinea pig(100727431) glycine receptor, beta
  • chicken(422411) glycine receptor, beta

Custom & Knockdown Gene Products

Small Molecule - Allosteric Modulator

Numero di prodotto
Descrizione
Specie
Isoflurane, ,
Specie
human
Halothane, United States Pharmacopeia (USP) Reference Standard,
Specie
human
2-Bromo-2-chloro-1,1,1-trifluoroethane, ≥99%,
Specie
human

Antibodies

Numero di prodotto
Descrizione
Reattività con
Applicazione
Anti-Glycine Receptor Antibody, Chemicon®, from rabbit,
Reattività con
human, mouse, rat
Applicazione
immunoprecipitation (IP)
western blot
Anti-GLRB antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Reattività con
human
Applicazione
immunohistochemistry

esiRNA

Numero di prodotto
Descrizione
Specie
MISSION® esiRNA, targeting mouse Glrb,
Specie
mouse
MISSION® esiRNA, targeting human GLRB,
Specie
human