Skip to Content
Merck
Get up to22% off for Pi Day through March 27.Save Now

GRIN2A

glutamate receptor, ionotropic, N-methyl D-aspartate 2A

Synonyms:
EPND, GluN2A, NMDAR2A, NR2A
Species:
Human GRIN2A (2903), Mouse Grin2a (14811), Rat Grin2a (24409), sheep GRIN2A (101106989), domestic guinea pig Grin2a (100727265), dog GRIN2A (490012), chicken GRIN2A (427678), domestic cat GRIN2A (101086110)
UniProtKB ID:
Q12879, O00669, Q17RZ6
Gene ID:
  • Human(2903) Summary: N-methyl-D-aspartate (NMDA) receptors are a class of ionotropic glutamate-gated ion channels. These receptors have been shown to be involved in long-term potentiation, an activity-dependent increase in the efficiency of synaptic transmission thought to underlie certain kinds of memory and learning. NMDA receptor channels are heteromers composed of the key receptor subunit NMDAR1 (GRIN1) and 1 or more of the 4 NMDAR2 subunits: NMDAR2A (GRIN2A), NMDAR2B (GRIN2B), NMDAR2C (GRIN2C) and NMDAR2D (GRIN2D). Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Aug 2008]
  • Mouse(14811) glutamate receptor, ionotropic, NMDA2A (epsilon 1)
  • Rat(24409) glutamate receptor, ionotropic, N-methyl D-aspartate 2A
  • sheep(101106989) glutamate receptor, ionotropic, N-methyl D-aspartate 2A
  • domestic guinea pig(100727265) glutamate receptor, ionotropic, N-methyl D-aspartate 2A
  • dog(490012) glutamate receptor, ionotropic, N-methyl D-aspartate 2A
  • chicken(427678) glutamate receptor, ionotropic, N-methyl D-aspartate 2A
  • domestic cat(101086110) glutamate receptor, ionotropic, N-methyl D-aspartate 2A

Custom & Knockdown Gene Products

  • siRNA

    Shop predesigned siRNA that are designed using the proprietary Rosetta Inpharmatics algorithm.

  • shRNA

    Shop the largest, most validated shRNA collection and build your own clone sets.

  • Custom Gene Products

    We offer a comprehensive portfolio of DNA oligos, RNA oligos and predesigned primers.

Small Molecule - Agonist

Product Number
Description
Species
239488
1,4-Bis(3-aminopropyl)piperazine, ≥95%,
Species
rat
1181007
Dextromethorphan hydrobromide, United States Pharmacopeia (USP) Reference Standard,
Species
human
D9684
Dextromethorphan hydrobromide, meets USP testing specifications,
Species
human
PHR1018
Dextromethorphan HBr, certified reference material,
Species
human
R1276
Reversin 121, ≥97% (HPLC), powder,
Species
mouse, rat, human

Small Molecule - Allosteric Modulator

Product Number
Description
Species
561479
4-Aminopiperidine, ,
Species
rat
Y0000450
Ketamine hydrochloride, European Pharmacopoeia (EP) Reference Standard,
Species
human
BP1172
Acamprosate calcium, British Pharmacopoeia (BP) Reference Standard,
Species
human
A6981
Acamprosate calcium, ≥98% (HPLC), powder,
Species
human
1000554
Acamprosate calcium, United States Pharmacopeia (USP) Reference Standard, monograph mol wt. 400.48 (C10H20CaN2O8S2),
Species
human

Small Molecule - Antagonist

Product Number
Description
Species
P8791
Polyglycine, mol wt 500-5,000,
Species
rat
S4264
Spermine, suitable for cell culture, BioReagent,
Species
rat, human
S3256
Spermine, ≥97%,
Species
rat, human
I5109
Indole-2-carboxylic acid, 98%,
Species
rat, human
1181007
Dextromethorphan hydrobromide, United States Pharmacopeia (USP) Reference Standard,
Species
human

Antibodies

Product Number
Description
Species Reactivity
Application
07-632
Anti-NR2A Antibody, Upstate®, from rabbit,
Species Reactivity
mouse, rat
Application
immunoprecipitation (IP)
western blot
SAB4501304
Anti-NMDAR2A antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
human, mouse, rat
Application
ELISA
immunofluorescence
immunohistochemistry
SAB5701191
Anti-NMDAR2A antibody produced in rabbit, ,
Species Reactivity
human, mouse, rat
Application
immunohistochemistry
western blot
SAB5200900
Monoclonal Anti-Glun2A/Nr2A - Fitc antibody produced in mouse, clone S327-95, purified immunoglobulin,
Species Reactivity
human, mouse, rat
Application
immunocytochemistry
immunohistochemistry
western blot
SAB5200892
Monoclonal Anti-Glun2A/Nr2A - Atto 594 antibody produced in mouse, clone S327-95, purified immunoglobulin,
Species Reactivity
human, mouse, rat
Application
immunocytochemistry
immunohistochemistry
western blot

Small Molecule - Blocker

Product Number
Description
Species
D8816
N-(3,3-Diphenylpropyl)glycinamide, >98% (HPLC), solid,
Species
human
Y0001181
Orphenadrine for peak identification, European Pharmacopoeia (EP) Reference Standard,
Species
human
75517
Orphenadrine hydrochloride, ≥98.0% (AT),
Species
human
Y0000100
Orphenadrine hydrochloride, European Pharmacopoeia (EP) Reference Standard,
Species
human
K3375
Kynurenic acid, ≥98%,
Species
rat, human

Small Molecule - Inhibitor

Product Number
Description
Species
I5109
Indole-2-carboxylic acid, 98%,
Species
rat, human
D207756
1,3-Diphenylguanidine, 97%,
Species
rat, mouse, human
N5501
Nω-Nitro-L-arginine, ≥98% (TLC),
Species
rat, mouse, human
P0547
Pentamidine isethionate salt, powder,
Species
human
324817
(Aminomethyl)phosphonic acid, 99%,
Species
rat, human

Small Molecule - Mixed Agonist/Antagonist

Product Number
Description
Species
534498
4-Piperidinopiperidine, 97%,
Species
rat
65690
3-(Methylamino)propylamine, technical, ≥97.0% (GC),
Species
rat
33262
1,3-Diamino-2-propanol, purum, ≥96.5% (GC),
Species
rat
D18609
1,3-Diamino-2-propanol, 95%,
Species
rat
115738
4-Amino-2,2,6,6-tetramethylpiperidine, 98%,
Species
rat

esiRNA

Product Number
Description
Species
EHU040271
MISSION® esiRNA, targeting human GRIN2A,
Species
human
EMU051581
MISSION® esiRNA, targeting mouse Grin2a,
Species
mouse