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Merck

GRIN2A

glutamate receptor, ionotropic, N-methyl D-aspartate 2A

Synonimy:
EPND, GluN2A, NMDAR2A, NR2A
Gatunek:
Human GRIN2A (2903), Mouse Grin2a (14811), Rat Grin2a (24409), sheep GRIN2A (101106989), domestic guinea pig Grin2a (100727265), dog GRIN2A (490012), chicken GRIN2A (427678), domestic cat GRIN2A (101086110)
Identyfikator UniProtKB:
Q12879, O00669, Q17RZ6
Identyfikator genu:
  • Human(2903) Summary: N-methyl-D-aspartate (NMDA) receptors are a class of ionotropic glutamate-gated ion channels. These receptors have been shown to be involved in long-term potentiation, an activity-dependent increase in the efficiency of synaptic transmission thought to underlie certain kinds of memory and learning. NMDA receptor channels are heteromers composed of the key receptor subunit NMDAR1 (GRIN1) and 1 or more of the 4 NMDAR2 subunits: NMDAR2A (GRIN2A), NMDAR2B (GRIN2B), NMDAR2C (GRIN2C) and NMDAR2D (GRIN2D). Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Aug 2008]
  • Mouse(14811) glutamate receptor, ionotropic, NMDA2A (epsilon 1)
  • Rat(24409) glutamate receptor, ionotropic, N-methyl D-aspartate 2A
  • sheep(101106989) glutamate receptor, ionotropic, N-methyl D-aspartate 2A
  • domestic guinea pig(100727265) glutamate receptor, ionotropic, N-methyl D-aspartate 2A
  • dog(490012) glutamate receptor, ionotropic, N-methyl D-aspartate 2A
  • chicken(427678) glutamate receptor, ionotropic, N-methyl D-aspartate 2A
  • domestic cat(101086110) glutamate receptor, ionotropic, N-methyl D-aspartate 2A

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Small Molecule - Agonist

Numer produktu
Opis
Gatunek
239488
1,4-Bis(3-aminopropyl)piperazine, ≥95%,
Gatunek
rat
D0740000
Dextromethorphan hydrobromide, European Pharmacopoeia (EP) Reference Standard,
Gatunek
human
PHR1018
Dextromethorphan HBr, certified reference material, pharmaceutical secondary standard,
Gatunek
human
1181007
Dekstrometorfan, United States Pharmacopeia (USP) Reference Standard,
Gatunek
human
D-013
Dextromethorphan solution, 1.0 mg/mL in methanol, ampule of 1 mL, certified reference material, Cerilliant®,
Gatunek
human

Small Molecule - Allosteric Modulator

Numer produktu
Opis
Gatunek
561479
4-Aminopiperidine, ,
Gatunek
rat
K1884
S-(+)-Ketamine hydrochloride, ,
Gatunek
human
Y0000450
Ketamine hydrochloride, European Pharmacopoeia (EP) Reference Standard,
Gatunek
human
K-002
Ketamine hydrochloride solution, 1.0 mg/mL in methanol (as free base), ampule of 1 mL, certified reference material, Cerilliant®,
Gatunek
human
K2753
(±)-Ketamine hydrochloride, solid,
Gatunek
human

Small Molecule - Antagonist

Numer produktu
Opis
Gatunek
G7403
Glycine, BioXtra, ≥99% (titration),
Gatunek
rat
G8790
Glycine, from non-animal source, meets EP, JP, USP testing specifications, suitable for cell culture, ≥98.5%,
Gatunek
rat
P8791
Polyglycine, mol wt 500-5,000,
Gatunek
rat
G5417
Glycine, ,
Gatunek
rat
180378
1-Adamantanemethylamine, 98%,
Gatunek
human

Antibodies

Numer produktu
Opis
Reaktywność gatunkowa
Zastosowanie
SAB2100974
Anti-GRIN2A antibody produced in rabbit, affinity isolated antibody,
Reaktywność gatunkowa
human
Zastosowanie
immunohistochemistry
western blot
ABN2251
Anti-phospho NMDAR2A (Ser1459), ,
Reaktywność gatunkowa
human
Zastosowanie
immunocytochemistry
western blot
MAB5572
Przeciwciało anty-NMDAR2A, ascites fluid, clone 2H9.24A6, Chemicon®,
Reaktywność gatunkowa
frog, human, mouse, rabbit, rat
Zastosowanie
western blot
SAB5200994
Monoklonalny anty-Glun2A/Nr2A- Rpe, clone S327A-38, purified immunoglobulin,
Reaktywność gatunkowa
human, mouse, rat
Zastosowanie
immunohistochemistry
western blot
SAB5200888
Monoklonalny anty-Glun2A/Nr2A, clone S327-95, purified immunoglobulin,
Reaktywność gatunkowa
human, mouse, rat
Zastosowanie
immunocytochemistry
immunohistochemistry
western blot

Small Molecule - Blocker

Numer produktu
Opis
Gatunek
D8816
N-(3,3-Diphenylpropyl)glycinamide, >98% (HPLC), solid,
Gatunek
human
A7127
Agmatine sulfate salt, ≥97%, powder,
Gatunek
human
Y0001181
Orphenadrine for peak identification, European Pharmacopoeia (EP) Reference Standard,
Gatunek
human
75517
Orphenadrine hydrochloride, ≥98.0% (AT),
Gatunek
human
Y0000100
Orphenadrine hydrochloride, European Pharmacopoeia (EP) Reference Standard,
Gatunek
human

Small Molecule - Inhibitor

Numer produktu
Opis
Gatunek
I5109
Indole-2-carboxylic acid, 98%,
Gatunek
rat, human
D207756
1,3-Diphenylguanidine, 97%,
Gatunek
rat, mouse, human
Q2128
Quisqualic acid, powder,
Gatunek
rat
N5501
Nω-Nitro-L-arginine, ≥98% (TLC),
Gatunek
rat, mouse, human
P0547
Pentamidine isethionate salt, powder,
Gatunek
human

Small Molecule - Mixed Agonist/Antagonist

Numer produktu
Opis
Gatunek
115738
4-Amino-2,2,6,6-tetramethylpiperidine, 98%,
Gatunek
rat
549983
N,N,N′,N′-Tetramethyl-1,3-propanediamine, ≥99%,
Gatunek
rat
33262
1,3-Diamino-2-propanol, purum, ≥96.5% (GC),
Gatunek
rat
308110
N,N′-Dimethyl-1,3-propanediamine, 97%,
Gatunek
rat
D18609
1,3-Diamino-2-propanol, 95%,
Gatunek
rat

esiRNA

Numer produktu
Opis
Gatunek
EMU051581
MISSION® esiRNA, targeting mouse Grin2a,
Gatunek
mouse
EHU040271
MISSION® esiRNA, targeting human GRIN2A,
Gatunek
human