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Merck

IDH3G

isocitrate dehydrogenase 3 (NAD+) gamma

Sinónimos:
H-IDHG
Especie:
Human IDH3G (3421), Mouse Idh3g (15929), Rat Idh3g (25179), cow IDH3G (614145), Zebrafish idh3g (550408), sheep IDH3G (101110910), Domestic Rabbit IDH3G (100328743), dog IDH3G (481081)
ID UniProtKB:
P51553, E9PDD5, Q9BUU5
ID del gen:
  • Human(3421) Summary: Isocitrate dehydrogenases catalyze the oxidative decarboxylation of isocitrate to 2-oxoglutarate. These enzymes belong to two distinct subclasses, one of which utilizes NAD(+) as the electron acceptor and the other NADP(+). Five isocitrate dehydrogenases have been reported: three NAD(+)-dependent isocitrate dehydrogenases, which localize to the mitochondrial matrix, and two NADP(+)-dependent isocitrate dehydrogenases, one of which is mitochondrial and the other predominantly cytosolic. NAD(+)-dependent isocitrate dehydrogenases catalyze the allosterically regulated rate-limiting step of the tricarboxylic acid cycle. Each isozyme is a heterotetramer that is composed of two alpha subunits, one beta subunit, and one gamma subunit. The protein encoded by this gene is the gamma subunit of one isozyme of NAD(+)-dependent isocitrate dehydrogenase. This gene is a candidate gene for periventricular heterotopia. Several alternatively spliced transcript variants of this gene have been described, but only some of their full length natures have been determined. [provided by RefSeq, Jul 2008]
  • Mouse(15929) isocitrate dehydrogenase 3 (NAD+), gamma
  • Rat(25179) isocitrate dehydrogenase 3 (NAD), gamma
  • cow(614145) isocitrate dehydrogenase 3 (NAD+) gamma
  • Zebrafish(550408) isocitrate dehydrogenase 3 (NAD+) gamma
  • sheep(101110910) isocitrate dehydrogenase 3 (NAD+) gamma
  • Domestic Rabbit(100328743) isocitrate dehydrogenase 3 (NAD+) gamma
  • dog(481081) isocitrate dehydrogenase 3 (NAD+) gamma

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esiRNA

Número de producto
Descripción
Especie
EHU066701
MISSION® esiRNA, targeting human IDH3G,
Especie
human