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Merck

IDH3G

isocitrate dehydrogenase 3 (NAD+) gamma

Sinónimos:
H-IDHG
Especie:
ID UniProtKB:
ID del gen:
  • Human(3421) Summary: Isocitrate dehydrogenases catalyze the oxidative decarboxylation of isocitrate to 2-oxoglutarate. These enzymes belong to two distinct subclasses, one of which utilizes NAD(+) as the electron acceptor and the other NADP(+). Five isocitrate dehydrogenases have been reported: three NAD(+)-dependent isocitrate dehydrogenases, which localize to the mitochondrial matrix, and two NADP(+)-dependent isocitrate dehydrogenases, one of which is mitochondrial and the other predominantly cytosolic. NAD(+)-dependent isocitrate dehydrogenases catalyze the allosterically regulated rate-limiting step of the tricarboxylic acid cycle. Each isozyme is a heterotetramer that is composed of two alpha subunits, one beta subunit, and one gamma subunit. The protein encoded by this gene is the gamma subunit of one isozyme of NAD(+)-dependent isocitrate dehydrogenase. This gene is a candidate gene for periventricular heterotopia. Several alternatively spliced transcript variants of this gene have been described, but only some of their full length natures have been determined. [provided by RefSeq, Jul 2008]
  • Mouse(15929) isocitrate dehydrogenase 3 (NAD+), gamma
  • Rat(25179) isocitrate dehydrogenase 3 (NAD), gamma
  • cow(614145) isocitrate dehydrogenase 3 (NAD+) gamma
  • Zebrafish(550408) isocitrate dehydrogenase 3 (NAD+) gamma
  • sheep(101110910) isocitrate dehydrogenase 3 (NAD+) gamma
  • Domestic Rabbit(100328743) isocitrate dehydrogenase 3 (NAD+) gamma
  • dog(481081) isocitrate dehydrogenase 3 (NAD+) gamma

Custom & Knockdown Gene Products

Antibodies

Número de producto
Descripción
Reactividad de especies
Aplicación
Anti-IDH3G antibody produced in rabbit, Ab1, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Reactividad de especies
human, mouse, rat
Aplicación
immunofluorescence
immunohistochemistry

western blot
Anti-IDH3G antibody produced in rabbit, Ab2, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Reactividad de especies
human, mouse, rat
Aplicación
immunofluorescence
immunohistochemistry

western blot
Anti-IDH3G antibody produced in goat, affinity isolated antibody, buffered aqueous solution,
Reactividad de especies
bovine, canine, human, mouse, pig, rat
Aplicación
ELISA
western blot

esiRNA

Número de producto
Descripción
Especie
MISSION® esiRNA, targeting human IDH3G,
Especie
human