LRRK2
leucine-rich repeat kinase 2
Synonymes:
AURA17, DARDARIN, PARK8, RIPK7, ROCO2
Espèce(s):
Human LRRK2 (120892), Mouse Lrrk2 (66725), Rat Lrrk2 (300160), Zebrafish lrrk2 (559366), dog LRRK2 (486608), cow LRRK2 (535652), domestic cat LRRK2 (101096157), sheep LRRK2 (101111447), naked mole-rat Lrrk2 (101708809), chicken LRRK2 (427844)
ID UniProtKB:
ID du gène:
- Human(120892) Summary: This gene is a member of the leucine-rich repeat kinase family and encodes a protein with an ankryin repeat region, a leucine-rich repeat (LRR) domain, a kinase domain, a DFG-like motif, a RAS domain, a GTPase domain, a MLK-like domain, and a WD40 domain. The protein is present largely in the cytoplasm but also associates with the mitochondrial outer membrane. Mutations in this gene have been associated with Parkinson disease-8. [provided by RefSeq, Jul 2008]
- Mouse(66725) leucine-rich repeat kinase 2
- Rat(300160) leucine-rich repeat kinase 2
- Zebrafish(559366) leucine-rich repeat kinase 2
- dog(486608) leucine-rich repeat kinase 2
- cow(535652) leucine-rich repeat kinase 2
- domestic cat(101096157) leucine-rich repeat kinase 2
- sheep(101111447) leucine-rich repeat kinase 2
- naked mole-rat(101708809) leucine-rich repeat kinase 2
- chicken(427844) leucine-rich repeat kinase 2
- domestic guinea pig(100730338) leucine-rich repeat kinase 2
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Antibodies
Numéro du produit
Description
Espèces réactives
Application
Anti-LRRK2 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Espèces réactives
human
Application
immunofluorescence
immunohistochemistry
western blot
immunohistochemistry
western blot
Anticorps anti-LRRK2, clone N138/6, clone N138/6, from mouse,
Espèces réactives
human, mouse
Application
immunohistochemistry
western blot
western blot
Anti-LRRK2 Antibody, from rabbit, purified by affinity chromatography,
Espèces réactives
human, mouse
Application
immunofluorescence
immunohistochemistry
immunoprecipitation (IP)
western blot
immunohistochemistry
immunoprecipitation (IP)
western blot
Anti-Phospho-LRRK2-S935 antibody produced in rabbit, ,
Espèces réactives
human, mouse, rat
Application
western blot
Anti-LRRK2/PARK8 Antibody, clone 1C17 ZooMAb® Rabbit Monoclonal, recombinant, expressed in HEK 293 cells,
Espèces réactives
bovine, canine, horse, human, monkey, mouse, porcine
Application
affinity binding assay
immunocytochemistry
immunohistochemistry
western blot
immunocytochemistry
immunohistochemistry
western blot
Proteins
Numéro du produit
Description
Espèce(s)
LRRK2 Protein, active, 10 µg, Active, N-terminal FLAG-tagged, recombinant, human LRRK2, amino acids 970-end. For use in Kinase Assays.,
Espèce(s)
human