MBTPS1
membrane-bound transcription factor peptidase, site 1
Synonyme:
PCSK8, S1P, SKI-1
Spezies:
Human MBTPS1 (8720), Mouse Mbtps1 (56453), Rat Mbtps1 (89842), sheep MBTPS1 (101101912), dog MBTPS1 (489684), domestic cat MBTPS1 (101081852), Horse MBTPS1 (100055849), chicken MBTPS1 (415704), Zebrafish mbtps1 (326710), domestic guinea pig Mbtps1 (100727902) ...Mehr
UniProtKB-ID:
Gen-ID:
- Human(8720) Summary: The encoded protein has a central role in the regulation of lipid metabolism in cells. It is a sterol-regulated subtilisin-like serine protease that cleaves ER membrane-bound sterol regulatory element-binding proteins (SREBPs), a reaction that initiates the two-step proteolytic process by which transcriptionally active fragments of SREBPs are released from the membrane for translocation to the nucleus. The gene product is an integral membrane ER protein, with the bulk located in the ER lumen. It is synthesized as an inactive preproprotein that is self-activated by an intramolecular cleavage that generates the mature protein. [provided by RefSeq, Jul 2008]
- Mouse(56453) membrane-bound transcription factor peptidase, site 1
- Rat(89842) membrane-bound transcription factor peptidase, site 1
- sheep(101101912) membrane-bound transcription factor peptidase, site 1
- dog(489684) membrane-bound transcription factor peptidase, site 1
- domestic cat(101081852) membrane-bound transcription factor peptidase, site 1
- Horse(100055849) membrane-bound transcription factor peptidase, site 1
- chicken(415704) membrane-bound transcription factor peptidase, site 1
- Zebrafish(326710) membrane-bound transcription factor protease, site 1
- domestic guinea pig(100727902) membrane-bound transcription factor peptidase, site 1
- naked mole-rat(101713902) membrane-bound transcription factor peptidase, site 1
- cow(511682) membrane-bound transcription factor peptidase, site 1
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Antibodies
Produktnummer
Beschreibung
Speziesreaktivität
Anwendung
Anti-MBTPS1 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Speziesreaktivität
human
Anwendung
immunohistochemistry