MCM3
minichromosome maintenance complex component 3
Synonyms:
HCC5, P1-MCM3, P1.h, RLFB
Species:
Human MCM3 (4172), Mouse Mcm3 (17215), Rat Mcm3 (316273), domestic cat MCM3 (101083515), fruit fly Mcm3 (31449), sheep MCM3 (101104435), chicken MCM3 (422043), Horse MCM3 (100069108), dog MCM3 (481839), Domestic Rabbit MCM3 (100339825) ...More
UniProtKB ID:
Gene ID:
- Human(4172) Summary: The protein encoded by this gene is one of the highly conserved mini-chromosome maintenance proteins (MCM) that are involved in the initiation of eukaryotic genome replication. The hexameric protein complex formed by MCM proteins is a key component of the pre-replication complex (pre_RC) and may be involved in the formation of replication forks and in the recruitment of other DNA replication related proteins. This protein is a subunit of the protein complex that consists of MCM2-7. It has been shown to interact directly with MCM5/CDC46. This protein also interacts with and is acetylated by MCM3AP, a chromatin-associated acetyltransferase. The acetylation of this protein inhibits the initiation of DNA replication and cell cycle progression. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2012]
- Mouse(17215) minichromosome maintenance deficient 3 (S. cerevisiae)
- Rat(316273) minichromosome maintenance complex component 3
- domestic cat(101083515) minichromosome maintenance complex component 3
- fruit fly(31449) Minichromosome maintenance 3
- sheep(101104435) minichromosome maintenance complex component 3
- chicken(422043) minichromosome maintenance complex component 3
- Horse(100069108) minichromosome maintenance complex component 3
- dog(481839) minichromosome maintenance complex component 3
- Domestic Rabbit(100339825) minichromosome maintenance complex component 3
- naked mole-rat(101719015) minichromosome maintenance complex component 3
- Zebrafish(100536986) minichromosome maintenance complex component 3
- Zebrafish(192323) MCM3 minichromosome maintenance deficient 3 (S. cerevisiae)
- cow(281302) minichromosome maintenance complex component 3
- domestic guinea pig(100729563) minichromosome maintenance complex component 3
- Thale Cress(834670) DNA replication licensing factor MCM3-like protein
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Antibodies
Product Number
Description
Species Reactivity
Application
Monoclonal Anti-MCM3, (C-terminal) antibody produced in mouse, clone 3E1, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human
Application
ELISA
immunofluorescence
western blot
immunofluorescence
western blot
Anti-MCM3 antibody produced in rabbit, Ab1, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human, mouse, rat
Application
immunohistochemistry
western blot
western blot
Anti-MCM3 antibody produced in rabbit, Ab2, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human, mouse, rat
Application
immunofluorescence
immunohistochemistry
western blot
immunohistochemistry
western blot
Anti-MCM3 antibody produced in rabbit, ,
Species Reactivity
human, mouse, rat
Application
immunohistochemistry
western blot
western blot
KD-Validated Anti MCM3 Antibody, clone 23GB2490, Rabbit Monoclonal, clone 23GB2490, recombinant rabbit monoclonal, expressed in HEK293 cells,
Species Reactivity
human, rat
Application
immunofluorescence
western blot
western blot