MLH1
mutL homolog 1
Sinonimi:
COCA2, FCC2, HNPCC, HNPCC2, hMLH1
Specie:
Human MLH1 (4292), Mouse Mlh1 (17350), Rat Mlh1 (81685), Thale Cress MLH1 (826493), fruit fly Mlh1 (35796), sheep MLH1 (101108344), domestic guinea pig Mlh1 (100717848), naked mole-rat Mlh1 (101698546), Domestic Rabbit MLH1 (100337912), Horse MLH1 (100050351) ...Più
ID UniProtKB:
ID gene:
- Human(4292) Summary: This gene was identified as a locus frequently mutated in hereditary nonpolyposis colon cancer (HNPCC). It is a human homolog of the E. coli DNA mismatch repair gene mutL, consistent with the characteristic alterations in microsatellite sequences (RER+phenotype) found in HNPCC. Alternative splicing results in multiple transcript variants encoding distinct isoforms. Additional transcript variants have been described, but their full-length natures have not been determined.[provided by RefSeq, Nov 2009]
- Mouse(17350) mutL homolog 1 (E. coli)
- Rat(81685) mutL homolog 1, colon cancer, nonpolyposis type 2 (E. coli)
- Thale Cress(826493) DNA mismatch repair protein MLH1
- fruit fly(35796) CG11482 gene product from transcript CG11482-RB
- sheep(101108344) mutL homolog 1, colon cancer, nonpolyposis type 2 (E. coli)
- domestic guinea pig(100717848) mutL homolog 1, colon cancer, nonpolyposis type 2 (E. coli)
- naked mole-rat(101698546) mutL homolog 1, colon cancer, nonpolyposis type 2 (E. coli)
- Domestic Rabbit(100337912) mutL homolog 1, colon cancer, nonpolyposis type 2 (E. coli)
- Horse(100050351) mutL homolog 1, colon cancer, nonpolyposis type 2 (E. coli)
- cow(533652) mutL homolog 1, colon cancer, nonpolyposis type 2 (E. coli)
- dog(477019) mutL homolog 1, colon cancer, nonpolyposis type 2 (E. coli)
- domestic cat(101089037) mutL homolog 1, colon cancer, nonpolyposis type 2 (E. coli)
- Zebrafish(393632) mutL homolog 1, colon cancer, nonpolyposis type 2 (E. coli)
- chicken(420729) mutL homolog 1, colon cancer, nonpolyposis type 2 (E. coli)
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Antibodies
Numero di prodotto
Descrizione
Reattività con
Applicazione
Monoclonal Anti-MLH1 antibody produced in mouse, clone M1, purified immunoglobulin, buffered aqueous solution,
Reattività con
human
Applicazione
ELISA
immunofluorescence
immunohistochemistry
proximity ligation assay
western blot
immunofluorescence
immunohistochemistry
proximity ligation assay
western blot
Anti-MLH1 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Reattività con
human
Applicazione
immunofluorescence
immunohistochemistry
immunohistochemistry
Anti-MLH1 Antibody, clone 1B15 ZooMAb® Rabbit Monoclonal, recombinant, expressed in HEK 293 cells,
Reattività con
human, monkey
Applicazione
affinity binding assay
immunocytochemistry
immunohistochemistry
western blot
immunocytochemistry
immunohistochemistry
western blot