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MMP1

matrix metallopeptidase 1 (interstitial collagenase)

Synonimy:
CLG, CLGN
Gatunek:
Identyfikator UniProtKB:
Identyfikator genu:
  • Human(4312) Summary: Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. This gene encodes a secreted enzyme which breaks down the interstitial collagens, types I, II, and III. The gene is part of a cluster of MMP genes which localize to chromosome 11q22.3. Alternative splicing results in multiple transcript variants.[provided by RefSeq, Mar 2009]
  • Rat(432357) matrix metalloproteinase 1
  • Rat(300339) matrix metallopeptidase 1 (interstitial collagenase)
  • domestic guinea pig(100727966) matrix metallopeptidase 1 (interstitial collagenase)
  • naked mole-rat(101697620) matrix metallopeptidase 1 (interstitial collagenase)
  • dog(489428) matrix metallopeptidase 1 (interstitial collagenase)
  • chicken(418982) matrix metallopeptidase 1 (interstitial collagenase)
  • sheep(101120355) matrix metallopeptidase 1 (interstitial collagenase)
  • fruit fly(37949) Matrix metalloproteinase 1
  • cow(281308) matrix metallopeptidase 1 (interstitial collagenase)
  • Horse(100033896) matrix metallopeptidase 1 (interstitial collagenase)
  • Domestic Rabbit(100009110) matrix metallopeptidase 1 (interstitial collagenase)

Custom & Knockdown Gene Products

ELISA

Numer produktu
Opis
Gatunek
Human MMP-1 ELISA Kit, for cell and tissue lysates,
Gatunek
human
Human MMP-1 ELISA Kit, for serum, plasma, cell culture supernatant and urine,
Gatunek
human

Antibodies

Numer produktu
Opis
Reaktywność gatunkowa
Zastosowanie
Anti-Matrix Metalloproteinase-1 antibody produced in goat, affinity isolated antibody, lyophilized powder,
Reaktywność gatunkowa
human
Zastosowanie
immunocytochemistry
immunohistochemistry

western blot
Anti-MMP-1 Antibody, hinge region, from rabbit, purified by affinity chromatography,
Reaktywność gatunkowa
human
Zastosowanie
western blot
Anty-MMP-1 (Ab-1) mysie mAb (41-1E5), liquid, clone 41-1E5, Calbiochem®,
Reaktywność gatunkowa
human
Zastosowanie
Anti-MMP-1 Antibody, a.a. 332-350 hMMP1, clone 41-1E5, clone 41-1E5, Chemicon®, from mouse,
Reaktywność gatunkowa
human, rabbit
Zastosowanie
ELISA
immunohistochemistry

western blot
Anti-MMP1 antibody produced in mouse, purified immunoglobulin, buffered aqueous solution,
Reaktywność gatunkowa
human
Zastosowanie
western blot

Small Molecule - Inhibitor

Numer produktu
Opis
Gatunek
Doxycycline monohydrate, ,
Gatunek
human
Monohydrat doksycykliny, United States Pharmacopeia (USP) Reference Standard,
Gatunek
human
2,2′:5′,2′′:5′′,2′′′-Quaterthiophene, 96%,
Gatunek
human, rat, mouse
PD166793 hydrate, ≥98% (HPLC),
Gatunek
human, rat, mouse
Marimastat, ≥98% (HPLC),
Gatunek
human, rat, mouse

Proteins

Numer produktu
Opis
Gatunek
Matrix Metalloproteinase-1 human, recombinant, expressed in NSO cells, >95% (SDS-PAGE), buffered aqueous solution,
Gatunek
human
MMP-1 human, recombinant, expressed in E. coli, ≥98% (SDS-PAGE), ≥98% (HPLC), suitable for cell culture,
Gatunek
human
Collagen Type I−FITC Conjugate from bovine skin, ~1 mg/mL, solution,
Gatunek
cow, rat, human, mouse

esiRNA

Numer produktu
Opis
Gatunek
MISSION® esiRNA, targeting human MMP1,
Gatunek
human