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Merck

NBL1

neuroblastoma 1, DAN family BMP antagonist

Synonymes:
D1S1733E, DAN, DAND1, NB, NO3
Espèce(s):
ID UniProtKB:
ID du gène:
  • Human(4681) Summary: This gene product is the founding member of the evolutionarily conserved CAN (Cerberus and DAN) family of proteins, which contain a domain resembling the CTCK (C-terminal cystine knot-like) motif found in a number of signaling molecules. These proteins are secreted, and act as BMP (bone morphogenetic protein) antagonists by binding to BMPs and preventing them from interacting with their receptors. They may thus play an important role during growth and development. Alternatively spliced transcript variants have been identified for this gene. Read-through transcripts between this locus and the upstream mitochondrial inner membrane organizing system 1 gene (GeneID 440574) have been observed. [provided by RefSeq, May 2013]
  • Mouse(17965) neuroblastoma, suppression of tumorigenicity 1
  • Rat(50594) neuroblastoma 1, DAN family BMP antagonist
  • dog(487403) neuroblastoma, suppression of tumorigenicity 1
  • domestic cat(101090533) neuroblastoma, suppression of tumorigenicity 1
  • Horse(100071893) neuroblastoma, suppression of tumorigenicity 1
  • cow(535280) neuroblastoma 1, DAN family BMP antagonist
  • chicken(373952) neuroblastoma, suppression of tumorigenicity 1
  • Zebrafish(404629) neuroblastoma, suppression of tumorigenicity 1
  • naked mole-rat(101708204) neuroblastoma 1, DAN family BMP antagonist
  • domestic guinea pig(100732484) neuroblastoma 1, DAN family BMP antagonist
  • sheep(101108197) neuroblastoma, suppression of tumorigenicity 1

Custom & Knockdown Gene Products

ELISA

Numéro du produit
Description
Espèce(s)
Human DAN ELISA Kit, for serum, plasma, cell culture supernatant and urine,
Espèce(s)
human

Antibodies

Numéro du produit
Description
Espèces réactives
Application
Anti-NBL1 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Espèces réactives
human
Application
immunohistochemistry

esiRNA

Numéro du produit
Description
Espèce(s)
MISSION® esiRNA, targeting mouse Nbl1,
Espèce(s)
mouse
MISSION® esiRNA, targeting human NBL1, MINOS1-NBL1,
Espèce(s)
human