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Merck

PDGFRA

platelet-derived growth factor receptor, alpha polypeptide

Sinonimi:
CD140A, PDGFR-2, PDGFR2, RHEPDGFRA
Specie:
ID UniProtKB:
ID gene:
  • Human(5156) Summary: This gene encodes a cell surface tyrosine kinase receptor for members of the platelet-derived growth factor family. These growth factors are mitogens for cells of mesenchymal origin. The identity of the growth factor bound to a receptor monomer determines whether the functional receptor is a homodimer or a heterodimer, composed of both platelet-derived growth factor receptor alpha and beta polypeptides. Studies suggest that this gene plays a role in organ development, wound healing, and tumor progression. Mutations in this gene have been associated with idiopathic hypereosinophilic syndrome, somatic and familial gastrointestinal stromal tumors, and a variety of other cancers. [provided by RefSeq, Mar 2012]
  • Mouse(18595) platelet derived growth factor receptor, alpha polypeptide
  • Rat(25267) platelet derived growth factor receptor, alpha polypeptide
  • chicken(395509) platelet-derived growth factor receptor, alpha polypeptide
  • domestic guinea pig(100726209) platelet-derived growth factor receptor, alpha polypeptide
  • cow(282301) platelet-derived growth factor receptor, alpha polypeptide
  • Zebrafish(386856) platelet derived growth factor receptor alpha
  • domestic cat(101090765) platelet-derived growth factor receptor, alpha polypeptide
  • sheep(101106012) platelet-derived growth factor receptor, alpha polypeptide
  • dog(442860) platelet-derived growth factor receptor, alpha polypeptide
  • Horse(100059815) platelet-derived growth factor receptor, alpha polypeptide
  • naked mole-rat(101697360) platelet-derived growth factor receptor, alpha polypeptide

Custom & Knockdown Gene Products

ELISA

Numero di prodotto
Descrizione
Specie
Phosphotyrosine PDGFRA / Platelet-derived Growth Factor Receptor Alpha ELISA Kit, ,
Specie
human
Human PDGF R α  ELISA Kit, for serum, plasma, cell culture supernatant and urine,
Specie
human

Antibodies

Numero di prodotto
Descrizione
Reattività con
Applicazione
Anti PDGFRA Antibody, clone 24GB1165, Rabbit Monoclonal, clone 24GB1165, recombinant rabbit monoclonal, expressed in HEK293 cells,
Reattività con
human
Applicazione
flow cytometry
western blot
Anti-PDGFR α antibody produced in rabbit, affinity isolated antibody,
Reattività con
human, mouse, rat
Applicazione
ELISA
immunofluorescence

immunohistochemistry

western blot
Anti-PDGFRα Antibody, Upstate®, from rabbit,
Reattività con
human, mouse
Applicazione
immunoprecipitation (IP)
western blot
Monoclonal Anti-PDGFRA antibody produced in mouse, clone 2D2-1A11, purified immunoglobulin, buffered aqueous solution,
Reattività con
human
Applicazione
ELISA
proximity ligation assay

western blot
Anti-CD140a Antibody, clone APA5, clone APA5, Chemicon®, from rat,
Reattività con
mouse
Applicazione
ELISA
flow cytometry

immunohistochemistry

western blot

Small Molecule - Inhibitor

Numero di prodotto
Descrizione
Specie
Tyrphostin A9, solid,
Specie
mouse, human
Pazopanib, ,
Specie
human
α-Sexithiophene, ,
Specie
human, rat

Proteins

Numero di prodotto
Descrizione
Specie
Platelet-Derived Growth Factor-AA human, PDGF-AA, recombinant, expressed in E. coli, lyophilized powder, suitable for cell culture,
Specie
human
PDGFRα Protein, active, 50 µg, Active, recombinant human PDGFRα, residues 550-end, containing an N-terminal His6-tag, for use in Kinase Assays.,
Specie
human
PDGFR-α (D842V), active, GST tagged human, PRECISIO®, recombinant, expressed in baculovirus infected Sf9 cells, ≥70% (SDS-PAGE), buffered aqueous glycerol solution,
Specie
human
PDGFR-α (T674I), active, GST tagged human, PRECISIO®, recombinant, expressed in baculovirus infected Sf9 cells, ≥70% (SDS-PAGE), buffered aqueous glycerol solution,
Specie
human
PDGFR α (550-end, V561D) Protein, active human, 250 µg, ,
Specie
human

esiRNA

Numero di prodotto
Descrizione
Specie
MISSION® esiRNA, targeting mouse Pdgfra,
Specie
mouse
MISSION® esiRNA, targeting human PDGFRA,
Specie
human