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Merck

PIK3CG

phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit gamma

Sinônimos:
PI3CG, PI3K, PI3Kgamma, PIK3, p110gamma, p120-PI3K
Espécies:
Human PIK3CG (5294), Mouse Pik3cg (30955), Rat Pik3cg (298947), Zebrafish pik3cg (406598), domestic guinea pig Pik3cg (100725386), Zebrafish pik3cg (564261), dog PIK3CG (483266), sheep PIK3CG (101102896), domestic cat PIK3CG (101096215), cow PIK3CG (530001) ...Mais
ID UniProtKB:
P48736, A4D0Q6, Q8IV23, Q9BZC8
ID do gene:
  • Human(5294) Summary: This gene encodes a protein that belongs to the pi3/pi4-kinase family of proteins. The gene product is an enzyme that phosphorylates phosphoinositides on the 3-hydroxyl group of the inositol ring. It is an important modulator of extracellular signals, including those elicited by E-cadherin-mediated cell-cell adhesion, which plays an important role in maintenance of the structural and functional integrity of epithelia. In addition to its role in promoting assembly of adherens junctions, the protein is thought to play a pivotal role in the regulation of cytotoxicity in NK cells. The gene is located in a commonly deleted segment of chromosome 7 previously identified in myeloid leukemias. [provided by RefSeq, Jul 2008]
  • Mouse(30955) phosphoinositide-3-kinase, catalytic, gamma polypeptide
  • Rat(298947) phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit gamma
  • Zebrafish(406598) phosphoinositide-3-kinase, catalytic, gamma polypeptide
  • domestic guinea pig(100725386) phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit gamma
  • Zebrafish(564261) phosphoinositide-3-kinase, catalytic, gamma polypeptide
  • dog(483266) phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit gamma
  • sheep(101102896) phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit gamma
  • domestic cat(101096215) phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit gamma
  • cow(530001) phosphoinositide-3-kinase, catalytic, gamma polypeptide
  • chicken(417706) phosphoinositide-3-kinase, catalytic, gamma polypeptide
  • naked mole-rat(101707055) phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit gamma

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Antibodies

Número do produto
Descrição
Reatividade de espécies
Aplicação
WH0005294M2
Monoclonal Anti-PIK3CG antibody produced in mouse, clone 2G3, purified immunoglobulin, buffered aqueous solution,
Reatividade de espécies
human
Aplicação
ELISA
immunofluorescence
proximity ligation assay
western blot
HPA069976
Anti-PIK3CG antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody,
Reatividade de espécies
human
Aplicação
immunofluorescence

Small Molecule - Inhibitor

Número do produto
Descrição
Espécies
W1628
Wortmannin, from Penicillium funiculosum, ≥98% (HPLC and TLC),
Espécies
human
W3144
Wortmannin, Ready Made Solution, from Penicillium funiculosum, ≥95% (HPLC),
Espécies
human

Proteins

Número do produto
Descrição
Espécies
P8615
Phosphoinositide 3-kinase p110γ human, ≥95% (SDS-PAGE), recombinant, expressed in baculovirus infected insect cells, buffered aqueous glycerol solution,
Espécies
human
14-558-M
PI3 Kinase (p120γ), 20 µg, For use in Kinase Assays.,
Espécies
human
SRP0237
PI3 kinase (p120g) Active human, recombinant, expressed in baculovirus infected insect cells, ≥90% (SDS-PAGE),
Espécies
human

esiRNA

Número do produto
Descrição
Espécies
EHU081631
MISSION® esiRNA, targeting human PIK3CG,
Espécies
human