PIK3CG
phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit gamma
Synonyms:
PI3CG, PI3K, PI3Kgamma, PIK3, p110gamma, p120-PI3K
Species:
Human PIK3CG (5294), Mouse Pik3cg (30955), Rat Pik3cg (298947), Zebrafish pik3cg (406598), domestic guinea pig Pik3cg (100725386), Zebrafish pik3cg (564261), dog PIK3CG (483266), sheep PIK3CG (101102896), domestic cat PIK3CG (101096215), cow PIK3CG (530001) ...More
UniProtKB ID:
Gene ID:
- Human(5294) Summary: This gene encodes a protein that belongs to the pi3/pi4-kinase family of proteins. The gene product is an enzyme that phosphorylates phosphoinositides on the 3-hydroxyl group of the inositol ring. It is an important modulator of extracellular signals, including those elicited by E-cadherin-mediated cell-cell adhesion, which plays an important role in maintenance of the structural and functional integrity of epithelia. In addition to its role in promoting assembly of adherens junctions, the protein is thought to play a pivotal role in the regulation of cytotoxicity in NK cells. The gene is located in a commonly deleted segment of chromosome 7 previously identified in myeloid leukemias. [provided by RefSeq, Jul 2008]
- Mouse(30955) phosphoinositide-3-kinase, catalytic, gamma polypeptide
- Rat(298947) phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit gamma
- Zebrafish(406598) phosphoinositide-3-kinase, catalytic, gamma polypeptide
- domestic guinea pig(100725386) phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit gamma
- Zebrafish(564261) phosphoinositide-3-kinase, catalytic, gamma polypeptide
- dog(483266) phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit gamma
- sheep(101102896) phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit gamma
- domestic cat(101096215) phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit gamma
- cow(530001) phosphoinositide-3-kinase, catalytic, gamma polypeptide
- chicken(417706) phosphoinositide-3-kinase, catalytic, gamma polypeptide
- naked mole-rat(101707055) phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit gamma
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