PNPO
pyridoxamine 5'-phosphate oxidase
Synonyms:
PDXPO
Species:
Human PNPO (55163), Mouse Pnpo (103711), Rat Pnpo (64533), chicken PNPO (100857383), cow PNPO (512573), sheep PNPO (101117174), naked mole-rat Pnpo (101702026), Zebrafish pnpo (402868), domestic cat PNPO (101085004), domestic guinea pig Pnpo (100718098)
UniProtKB ID:
Gene ID:
- Human(55163) Summary: The enzyme encoded by this gene catalyzes the terminal, rate-limiting step in the synthesis of pyridoxal 5'-phosphate, also known as vitamin B6. Vitamin B6 is a required co-factor for enzymes involved in both homocysteine metabolism and synthesis of neurotransmitters such as catecholamine. Mutations in this gene result in pyridoxamine 5'-phosphate oxidase (PNPO) deficiency, a form of neonatal epileptic encephalopathy. [provided by RefSeq, Oct 2008]
- Mouse(103711) pyridoxine 5'-phosphate oxidase
- Rat(64533) pyridoxamine 5'-phosphate oxidase
- chicken(100857383) pyridoxamine 5'-phosphate oxidase
- cow(512573) pyridoxamine 5'-phosphate oxidase
- sheep(101117174) pyridoxamine 5'-phosphate oxidase
- naked mole-rat(101702026) pyridoxamine 5'-phosphate oxidase
- Zebrafish(402868) pyridoxine 5'-phosphate oxidase
- domestic cat(101085004) pyridoxamine 5'-phosphate oxidase
- domestic guinea pig(100718098) pyridoxamine 5'-phosphate oxidase
- dog(480540) pyridoxamine 5'-phosphate oxidase
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