PTPN7
protein tyrosine phosphatase, non-receptor type 7
Synonyme:
BPTP-4, HEPTP, LC-PTP, LPTP, PTPNI
Spezies:
Human PTPN7 (5778), Mouse Ptpn7 (320139), Rat Ptpn7 (246781), cow PTPN7 (614077), sheep PTPN7 (101114718), domestic guinea pig Ptpn7 (100723664), naked mole-rat Ptpn7 (101715531), chicken PTPN7 (770905), dog PTPN7 (607227), Horse PTPN7 (100052261)
UniProtKB-ID:
Gen-ID:
- Human(5778) Summary: The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This gene is preferentially expressed in a variety of hematopoietic cells, and is an early response gene in lymphokine stimulated cells. The non-catalytic N-terminus of this PTP can interact with MAP kinases and suppress the MAP kinase activities. This PTP was shown to be involved in the regulation of T cell antigen receptor (TCR) signaling, which was thought to function through dephosphorylating the molecules related to MAP kinase pathway. Multiple alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Dec 2010]
- Mouse(320139) protein tyrosine phosphatase, non-receptor type 7
- Rat(246781) protein tyrosine phosphatase, non-receptor type 7
- cow(614077) protein tyrosine phosphatase, non-receptor type 7
- sheep(101114718) protein tyrosine phosphatase, non-receptor type 7
- domestic guinea pig(100723664) protein tyrosine phosphatase, non-receptor type 7
- naked mole-rat(101715531) protein tyrosine phosphatase, non-receptor type 7
- chicken(770905) protein tyrosine phosphatase, non-receptor type 7
- dog(607227) protein tyrosine phosphatase, non-receptor type 7
- Horse(100052261) protein tyrosine phosphatase, non-receptor type 7
- domestic cat(101098110) protein tyrosine phosphatase, non-receptor type 7
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Antibodies
Produktnummer
Beschreibung
Speziesreaktivität
Anwendung
Anti-PTPN7 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Speziesreaktivität
human
Anwendung
immunohistochemistry
Anti-PTPN7 antibody produced in rabbit, purified immunoglobulin, buffered aqueous solution,
Speziesreaktivität
human
Anwendung
proximity ligation assay
western blot
western blot