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Merck

SCN7A

sodium channel, voltage-gated, type VII, alpha subunit

Sinonimi:
NaG, Nav2.1, Nav2.2, SCN6A
Specie:
ID UniProtKB:
ID gene:
  • Human(6332) Summary: This gene encodes one of the many voltage-gated sodium channel proteins. For proper functioning of neurons and muscles during action potentials, voltage-gated sodium channels direct sodium ion diffusion for membrane depolarization. This sodium channel protein has some atypical characteristics; the similarity between the human and mouse proteins is lower compared to other orthologous sodium channel pairs. Also, the S4 segments, which sense voltage changes, have fewer positive charged residues that in other sodium channels; domain 4 has fewer arginine and lysine residues compared to other sodium channel proteins. Several alternatively spliced transcript variants exist, but the full-length natures of all of them remain unknown. [provided by RefSeq, Dec 2011]
  • Mouse(20272) sodium channel, voltage-gated, type VII, alpha
  • Rat(64155) sodium channel, voltage-gated, type VII, alpha
  • naked mole-rat(101711842) sodium channel, voltage-gated, type VII, alpha subunit
  • domestic guinea pig(100715553) sodium channel, voltage-gated, type VII, alpha subunit
  • dog(488382) sodium channel, voltage-gated, type VII, alpha subunit
  • Horse(100062186) sodium channel, voltage-gated, type VII, alpha subunit
  • cow(507516) sodium channel, voltage-gated, type VII, alpha subunit
  • sheep(101109522) sodium channel, voltage-gated, type VII, alpha subunit
  • domestic cat(101082080) sodium channel, voltage-gated, type VII, alpha subunit

Custom & Knockdown Gene Products

Antibodies

Numero di prodotto
Descrizione
Reattività con
Applicazione
Anti-SCN7A antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Reattività con
human
Applicazione
immunohistochemistry
Anti-SCN7A antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Reattività con
human
Applicazione
immunofluorescence
immunohistochemistry

Small Molecule - Blocker

Numero di prodotto
Descrizione
Specie
Lidocaine hydrochloride, Pharmaceutical Secondary Standard; Certified Reference Material,
Specie
human
Lidocaine, Pharmaceutical Secondary Standard; Certified Reference Material,
Specie
human
Lidocaine hydrochloride monohydrate, solid,
Specie
human
Procaine hydrochloride, ≥97%,
Specie
human
Lidocaine, United States Pharmacopeia (USP) Reference Standard,
Specie
human

esiRNA

Numero di prodotto
Descrizione
Specie
MISSION® esiRNA, targeting mouse Scn7a,
Specie
mouse