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Merck

SIGMAR1

sigma non-opioid intracellular receptor 1

Sinonimi:
ALS16, OPRS1, SIG-1R, SR-BP, SR-BP1, SRBP, hSigmaR1, sigma1R
Specie:
ID UniProtKB:
ID gene:
  • Human(10280) Summary: This gene encodes a receptor protein that interacts with a variety of psychotomimetic drugs, including cocaine and amphetamines. The receptor is believed to play an important role in the cellular functions of various tissues associated with the endocrine, immune, and nervous systems. As indicated by its previous name, opioid receptor sigma 1 (OPRS1), the product of this gene was erroneously thought to function as an opioid receptor; it is now thought to be a non-opioid receptor. Alternative splicing of this gene results in transcript variants encoding distinct isoforms. [provided by RefSeq, Dec 2008]
  • Mouse(18391) sigma non-opioid intracellular receptor 1
  • Rat(29336) sigma non-opioid intracellular receptor 1
  • domestic guinea pig(100135589) sigma non-opioid intracellular receptor 1
  • cow(538903) sigma non-opioid intracellular receptor 1
  • sheep(101116710) sigma non-opioid intracellular receptor 1
  • domestic cat(101084912) sigma non-opioid intracellular receptor 1
  • Zebrafish(393952) sigma non-opioid intracellular receptor 1
  • chicken(100859748) sigma non-opioid intracellular receptor 1
  • dog(481587) sigma non-opioid intracellular receptor 1
  • naked mole-rat(101707150) sigma non-opioid intracellular receptor 1

Custom & Knockdown Gene Products

Small Molecule - Agonist

Numero di prodotto
Descrizione
Specie
Dextromethorphan HBr, certified reference material,
Specie
human
Dextromethorphan solution, 1.0 mg/mL in methanol, ampule of 1 mL, certified reference material, Cerilliant®,
Specie
human
Dextromethorphan hydrobromide, United States Pharmacopeia (USP) Reference Standard,
Specie
human
Dextromethorphan hydrobromide, meets USP testing specifications,
Specie
human
Dextromethorphan hydrobromide, European Pharmacopoeia (EP) Reference Standard,
Specie
human

Small Molecule - Allosteric Modulator

Numero di prodotto
Descrizione
Specie
Pentazocine solution, 1.0 mg/mL in methanol, ampule of 1 mL, certified reference material, Cerilliant®,
Specie
human

Antibodies

Numero di prodotto
Descrizione
Reattività con
Applicazione
Anti-SIGMAR1 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Reattività con
human
Applicazione
immunohistochemistry
Anti-Sigma IR Antibody, clone ICR-SIG1R-A, clone ICR-SIG1R-A, from rat,
Reattività con
human, mouse
Applicazione
flow cytometry
immunocytochemistry

immunohistochemistry

immunoprecipitation (IP)

western blot
ANTI-OPRS1 (CENTER) antibody produced in rabbit, purified immunoglobulin, buffered aqueous solution,
Reattività con
human, mouse
Applicazione
western blot

esiRNA

Numero di prodotto
Descrizione
Specie
MISSION® esiRNA, targeting mouse Sigmar1,
Specie
mouse