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SIRT2

sirtuin 2

Synonimy:
SIR2, SIR2L, SIR2L2
Gatunek:
Identyfikator UniProtKB:
Identyfikator genu:
  • Human(22933) Summary: This gene encodes a member of the sirtuin family of proteins, homologs to the yeast Sir2 protein. Members of the sirtuin family are characterized by a sirtuin core domain and grouped into four classes. The functions of human sirtuins have not yet been determined; however, yeast sirtuin proteins are known to regulate epigenetic gene silencing and suppress recombination of rDNA. Studies suggest that the human sirtuins may function as intracellular regulatory proteins with mono-ADP-ribosyltransferase activity. The protein encoded by this gene is included in class I of the sirtuin family. Several transcript variants are resulted from alternative splicing of this gene. [provided by RefSeq, Jul 2010]
  • Mouse(64383) sirtuin 2
  • Rat(361532) sirtuin 2
  • dog(612558) sirtuin 2
  • chicken(548628) sirtuin 2
  • domestic guinea pig(100734519) sirtuin 2
  • cow(504463) sirtuin 2
  • Zebrafish(322309) sirtuin 2 (silent mating type information regulation 2, homolog) 2 (S. cerevisiae)
  • sheep(101113169) sirtuin 2
  • domestic cat(101099513) sirtuin 2
  • fruit fly(42414) CG5085 gene product from transcript CG5085-RA
  • naked mole-rat(101715152) sirtuin 2

Custom & Knockdown Gene Products

ELISA

Numer produktu
Opis
Gatunek
Human Sirtuin 2 ELISA, for serum, plasma and cell culture supernatants,
Gatunek
human

Small Molecule - Antagonist

Numer produktu
Opis
Gatunek
Sirtinol, ≥95% (HPLC),
Gatunek
human
Nicotinamide, BioReagent, suitable for cell culture, suitable for insect cell culture,
Gatunek
human
Nicotinamide, ≥99.5% (HPLC),
Gatunek
human
Nicotinamide, ≥98% (HPLC), powder,
Gatunek
human
Niacinamide, meets USP testing specifications,
Gatunek
human

Antibodies

Numer produktu
Opis
Reaktywność gatunkowa
Zastosowanie
Anti-SIRT2 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Reaktywność gatunkowa
human
Zastosowanie
ChIP
immunofluorescence

immunohistochemistry
Anti-SIRT2 Antibody, clone 1D4 ZooMAb® Rabbit Monoclonal, recombinant, expressed in HEK 293 cells,
Reaktywność gatunkowa
human
Zastosowanie
affinity binding assay
immunohistochemistry

western blot
Przeciwciało anty-SIRT2, klon 1E1U3, królicze monoklonalne, ,
Reaktywność gatunkowa
human
Zastosowanie
western blot
Anti-SIRT2 Antibody, clone 7G5, ,
Reaktywność gatunkowa
human
Zastosowanie
immunoprecipitation (IP)
western blot
Przeciwciało anty-SIRT2, from rabbit, purified by affinity chromatography,
Reaktywność gatunkowa
human, mouse
Zastosowanie
immunoprecipitation (IP)
western blot

Proteins

Numer produktu
Opis
Gatunek
Sirtuin 2 human, recombinant, expressed in E. coli, ≥80% (SDS-PAGE),
Gatunek
human

esiRNA

Numer produktu
Opis
Gatunek
MISSION® esiRNA, targeting human SIRT2,
Gatunek
human
MISSION® esiRNA, targeting mouse Sirt2,
Gatunek
mouse