TNFSF10
tumor necrosis factor (ligand) superfamily, member 10
Synonimy:
APO2L, Apo-2L, CD253, TL2, TRAIL
Gatunek:
Human TNFSF10 (8743), Mouse Tnfsf10 (22035), Rat Tnfsf10 (246775), naked mole-rat Tnfsf10 (101702439), domestic guinea pig Tnfsf10 (100734497), cow TNFSF10 (507215), sheep TNFSF10 (101114153), domestic cat TNFSF10 (101083289), domestic cat TNFSF10 (100174789), dog TNFSF10 (100174780) ...Więcej
Identyfikator UniProtKB:
Identyfikator genu:
- Human(8743) Summary: The protein encoded by this gene is a cytokine that belongs to the tumor necrosis factor (TNF) ligand family. This protein preferentially induces apoptosis in transformed and tumor cells, but does not appear to kill normal cells although it is expressed at a significant level in most normal tissues. This protein binds to several members of TNF receptor superfamily including TNFRSF10A/TRAILR1, TNFRSF10B/TRAILR2, TNFRSF10C/TRAILR3, TNFRSF10D/TRAILR4, and possibly also to TNFRSF11B/OPG. The activity of this protein may be modulated by binding to the decoy receptors TNFRSF10C/TRAILR3, TNFRSF10D/TRAILR4, and TNFRSF11B/OPG that cannot induce apoptosis. The binding of this protein to its receptors has been shown to trigger the activation of MAPK8/JNK, caspase 8, and caspase 3. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2010]
- Mouse(22035) tumor necrosis factor (ligand) superfamily, member 10
- Rat(246775) tumor necrosis factor (ligand) superfamily, member 10
- naked mole-rat(101702439) tumor necrosis factor (ligand) superfamily, member 10
- domestic guinea pig(100734497) tumor necrosis factor (ligand) superfamily, member 10
- cow(507215) tumor necrosis factor (ligand) superfamily, member 10
- sheep(101114153) tumor necrosis factor (ligand) superfamily, member 10
- domestic cat(101083289) tumor necrosis factor (ligand) superfamily, member 10
- domestic cat(100174789) tumor necrosis factor (ligand) superfamily, member 10
- dog(100174780) tumor necrosis factor (ligand) superfamily, member 10
- Zebrafish(436866) tumor necrosis factor (ligand) superfamily, member 10
- chicken(378894) tumor necrosis factor (ligand) superfamily, member 10
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ELISA
Antibodies
Numer produktu
Opis
Reaktywność gatunkowa
Zastosowanie
Anti-TNFSF10 antibody produced in rabbit, affinity isolated antibody,
Reaktywność gatunkowa
human
Zastosowanie
western blot
Anti-TNFSF10 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Reaktywność gatunkowa
human
Zastosowanie
immunofluorescence
immunohistochemistry
immunohistochemistry
Przeciwciało anty-sTRAIL, klon III6F, clone III6F, from mouse,
Reaktywność gatunkowa
human
Zastosowanie
flow cytometry
immunohistochemistry
immunoprecipitation (IP)
immunohistochemistry
immunoprecipitation (IP)
Przeciwciało anty-TRAIL/CD253, klon 6D12.2, clone 6D12.2, from mouse,
Reaktywność gatunkowa
human
Zastosowanie
flow cytometry
immunohistochemistry
immunohistochemistry
Przeciwciało monoklonalne anty-CD253wytwarzane u myszy, clone 2E5,
Reaktywność gatunkowa
human
Zastosowanie
flow cytometry
Proteins
Numer produktu
Opis
Gatunek
TRAIL, Soluble mouse, recombinant, expressed in E. coli, His tagged, >95% (SDS-PAGE),
Gatunek
mouse
TRAIL, Soluble human, recombinant, expressed in E. coli, His tagged, >98% (SDS-PAGE),
Gatunek
human
TRAIL from mouse, recombinant, expressed in E. coli, ≥95% (SDS-PAGE), ≥95% (HPLC), suitable for cell culture,
Gatunek
mouse
TRAIL human, recombinant, expressed in E. coli, ≥98% (SDS-PAGE and HPLC), lyophilized powder,
Gatunek
human
TRAIL human, recombinant, expressed in NSO cells, >97% (SDS-PAGE), lyophilized powder,
Gatunek
human