TPMT
thiopurine S-methyltransferase
Synonyms:
Species:
Human TPMT (7172), Mouse Tpmt (22017), Rat Tpmt (690050), domestic guinea pig Tpmt (100722156), sheep TPMT (101123418), Domestic Rabbit TPMT (100009411), cow TPMT (511644), naked mole-rat Tpmt (101703237), dog TPMT (403536), domestic cat TPMT (493759) ...More
UniProtKB ID:
Gene ID:
- Human(7172) Summary: This gene encodes the enzyme that metabolizes thiopurine drugs via S-adenosyl-L-methionine as the S-methyl donor and S-adenosyl-L-homocysteine as a byproduct. Thiopurine drugs such as 6-mercaptopurine are used as chemotherapeutic agents. Genetic polymorphisms that affect this enzymatic activity are correlated with variations in sensitivity and toxicity to such drugs within individuals. A pseudogene for this locus is located on chromosome 18q. [provided by RefSeq, Jul 2008]
- Mouse(22017) thiopurine methyltransferase
- Rat(690050) thiopurine S-methyltransferase
- domestic guinea pig(100722156) thiopurine S-methyltransferase
- sheep(101123418) thiopurine S-methyltransferase
- Domestic Rabbit(100009411) thiopurine S-methyltransferase
- cow(511644) thiopurine S-methyltransferase
- naked mole-rat(101703237) thiopurine S-methyltransferase
- dog(403536) thiopurine S-methyltransferase
- domestic cat(493759) thiopurine S-methyltransferase
- Horse(100034066) thiopurine S-methyltransferase
- chicken(420830) thiopurine S-methyltransferase
- Goat(100860988) thiopurine S-methyltransferase
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Antibodies
Product Number
Description
Species Reactivity
Application
Anti-TPMT antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunohistochemistry
western blot
western blot
Anti-TPMT antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunofluorescence
immunohistochemistry
western blot
immunohistochemistry
western blot
Anti Thiopurine S-Methyltransferase Antibody, clone 24GB1895, Rabbit Monoclonal, clone 24GB1895, recombinant rabbit monoclonal, expressed in HEK293 cells,
Species Reactivity
human, rat
Application
flow cytometry
immunofluorescence
western blot
immunofluorescence
western blot