902071
Carboxylic acid poly(ethylene glycol)-block-poly(lactide-co-glycolide)
PEG average Mn 5000, PLGA average Mn 15000, lactide:glycolide (50:50)
Synonym(s):
Carboxylic acid-PEG-b-PLGA, Carboxylic acid-PEG-PLGA
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About This Item
Linear Formula:
C6H11O3S(C2H4O)nC2H4O[(C2H2O2)x(C3H4O2)y]mH
NACRES:
NA.23
UNSPSC Code:
12352106
description
Identity: Conforms to structure (by NMR)
form
powder
feed ratio
lactide:glycolide (50:50), lactide:glycolide:5 (50:50(by NMR))
mol wt
PEG Mn 4000-7000 g/mol (by NMR), PEG average Mn 5000, PLGA Mn 13000-18000 g/mol (by NMR), PLGA average Mn 15000
color
white
storage temp.
−20°C
Application
Carboxylic acid poly(ethylene glycol)-block-poly(lactide-co-glycolide) is a carboxylic acid-functionalized, biocompatible, amphiphilic block copolymer. Due to its self-assembling properties, this material can be used in the formation of nanoparticles for drug delivery. Additionally, due to the carboxylic acid-functionalization of the PEG block, this material can be used to rapidly covalently conjugate biomolecules, API, or targeting ligands. Potential uses include the targeted and/or controlled release of cancer drugs, anti-inflammatory drugs, antibiotics, or anesthetic agents.
Storage Class
11 - Combustible Solids
WGK
WGK 3
Flash Point (°F)
Not applicable
Flash Point (°C)
Not applicable
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