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890820C

Avanti

18:0 DAP

Avanti Research™ - A Croda Brand

Synonym(s):

1,2-distearoyl-3-dimethylammonium-propane

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About This Item

Empirical Formula (Hill Notation):
C41H81NO4
CAS Number:
121315-93-3
Molecular Weight:
652.09
UNSPSC Code:
12352211
NACRES:
NA.25
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Product Name

18:0 DAP, Avanti Research™ - A Croda Brand 890820C

assay

>99% (TLC)

form

liquid

packaging

pkg of 1 × 2.5 mL (890820C-25mg)

manufacturer/tradename

Avanti Research™ - A Croda Brand 890820C

concentration

10 mg/mL (890820C-25mg)

lipid type

transfection
cationic lipids

shipped in

dry ice

storage temp.

−20°C

SMILES string

[H]C(CN(C)C)(OC(CCCCCCCCCCCCCCCCC)=O)COC(CCCCCCCCCCCCCCCCC)=O

InChI

1S/C41H81NO4/c1-5-7-9-11-13-15-17-19-21-23-25-27-29-31-33-35-40(43)45-38-39(37-42(3)4)46-41(44)36-34-32-30-28-26-24-22-20-18-16-14-12-10-8-6-2/h39H,5-38H2,1-4H3

InChI key

RVBUSVJSKGVQQS-UHFFFAOYSA-N

Application

1,2-distearoyl-3-dimethylammonium-propane (18:0 DAP) might be used to formulate lipid nanoparticles (LNPs) and to test its efficiency of packaging mRNA into an LNP. It might also be used in the preparation of “bubble liposomes” (BLs).

Biochem/physiol Actions

1,2-distearoyl-3-dimethylammonium-propane (18:0 DAP) is a cationic lipid and serves as a pH-sensitive transfection reagent.

Packaging

5 mL Clear Glass Sealed Ampule (890820C-25mg)

Legal Information

Avanti Research is a trademark of Avanti Polar Lipids, LLC

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Pictograms

Skull and crossbonesHealth hazard
GHS06,GHS08

Signal Word

Danger

Hazard Classifications

Acute Tox. 3 Inhalation - Acute Tox. 4 Oral - Carc. 2 - Eye Irrit. 2 - Repr. 2 - Skin Irrit. 2 - STOT RE 1 - STOT SE 3

Target Organs

Central nervous system

WGK

WGK 3

Storage Class

6.1D - Non-combustible acute toxic Cat.3 / toxic hazardous materials or hazardous materials causing chronic effects

Flash Point (°F)

does not flash

Flash Point (°C)

does not flash

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