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SML1929

Equisetin

Name: Equisetin
Brand: SIGMA

(Fusarium equiseti), ≥97% (HPLC)

別名:

(3E,5S)-3-[[(1S,2R,4aS,6R,8aR)-1,6-dimethyl-2-[(E)-prop-1-enyl]-4a,5,6,7,8,8a-hexahydro-2H-naphthalen-1-yl]-hydroxymethylidene]-5-(hydroxymethyl)-1-methylpyrrolidine-2,4-dione

で組織・契約価格をご覧ください。

この商品について

実験式（ヒル表記法）:

C₂₂H₃₁NO₄

CAS番号:

57749-43-6

分子量:

373.49

NACRES:

NA.77

UNSPSC Code:

12352200

Assay:

≥97% (HPLC)

Form:

powder

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特性

Quality Segment

200

biological source

(Fusarium equiseti)

assay

≥97% (HPLC)

form

powder

solubility

DMSO: soluble 1 mg/mL, chloroform: soluble 5 mg/mL

shipped in

ambient

storage temp.

−20°C

SMILES string

C[C@H]1C[C@]2([H])[C@@]([C@](C)(/C(O)=C3C([C@H](CO)N(C)C/3=O)=O)[C@H](/C=C/C)C=C2)([H])CC1

InChI

1S/C22H31NO4/c1-5-6-15-9-8-14-11-13(2)7-10-16(14)22(15,3)20(26)18-19(25)17(12-24)23(4)21(18)27/h5-6,8-9,13-17,24,27H,7,10-12H2,1-4H3/b6-5+/t13-,14-,15-,16-,17+,22-/m1/s1

InChI key

SLOQQJFOWFUUMP-KNQICWOTSA-N

詳細

Biochem/physiol Actions

Equisetin is a tetramic acid analog derived from Fusarium equisti. Equisetin is mainly known for its antibiotic and cytotoxic activity and for its inhibitory effect on HIV-1 integrase. Inhibition of HIV integrase by Equisetin was reported with IC₅₀ values of 5-20 μM. Moreover, it was shown that Equisetin specifically inhibits the substrate anion carriers of the inner membrane of mitochondria and acts nonspecifically on protein membranes and protein hydrophobic domains. In addition, it was demonstrated that Equisetin causes phytotoxicity by causing root Necrosis and was also identified in a mycotoxin cocktail associated with cattle feeding problems.

Equisetin is a tetramic acid analog derived from Fusarium equisti.

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当該品目	SML1894	SML2395	SML1877
Sigma-Aldrich SML1929 Equisetin	Sigma-Aldrich SML1894 SYP-5	Sigma-Aldrich SML2395 Elocalcitol	Sigma-Aldrich SML1877 タダラフィル
form powder	form powder	form powder	form powder
assay ≥97% (HPLC)	assay ≥98% (HPLC)	assay ≥98% (HPLC)	assay ≥98% (HPLC)
Quality Level 200	Quality Level 100	Quality Level -	Quality Level 100
storage temp. −20°C	storage temp. 2-8°C	storage temp. −20°C	storage temp. −20°C
solubility DMSO: soluble 1 mg/mL, chloroform: soluble 5 mg/mL	solubility DMSO: 20 mg/mL, clear	solubility DMSO: 2 mg/mL, clear	solubility DMSO: 20 mg/mL, clear
biological source (Fusarium equiseti)	biological source -	biological source -	biological source -

保管分類

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

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試験成績書（COA）

Lot/Batch Number

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