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SML2243

BTSA1

≥98% (HPLC)

Synonym(s):

3-Phenyl-1-(4-phenyl-2-thiazolyl)-1H-pyrazole-4,5-dione 4-[2-(2-thiazolyl)hydrazone]

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About This Item

Empirical Formula (Hill Notation):
C21H14N6OS2
CAS Number:
Molecular Weight:
430.51
UNSPSC Code:
12352200
NACRES:
NA.77
Assay:
≥98% (HPLC)
Form:
powder


assay

≥98% (HPLC)

form

powder

color

red to dark red-brown

solubility

DMSO: 2 mg/mL, clear (warmed)

storage temp.

2-8°C

SMILES string

O=C1N(C2=NC(C3=CC=CC=C3)=CS2)N=C(C4=CC=CC=C4)/C1=N\NC5=NC=CS5

InChI key

KYVZVVOQWWCVPP-HKOYGPOVSA-N

Biochem/physiol Actions

BTSA1 is orally available, highly specific and potent BAX activator that binds to N-terminal activation site of Bax and induces conformational changes. BTSA1 potently induces apoptosis in leukemia cell lines and patient samples while sparing healthy cells.
orally available, highly specific and potent BAX activator that binds to N-terminal activation site of Bax

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This Item
SML0870SML1355SML2118
description

≥98% (HPLC)

description

≥98% (HPLC)

description

≥98% (HPLC)

description

≥98% (HPLC)

assay

≥98% (HPLC)

assay

≥98% (HPLC)

assay

≥98% (HPLC)

assay

≥98% (HPLC)

form

powder

form

powder

form

powder

form

powder

storage temp.

2-8°C

storage temp.

2-8°C

storage temp.

2-8°C

storage temp.

2-8°C

solubility

DMSO: 2 mg/mL, clear (warmed)

solubility

DMSO: 20 mg/mL, clear

solubility

DMSO: 5 mg/mL, clear (warmed)

solubility

DMSO: 2 mg/mL, clear

color

red to dark red-brown

color

white to beige

color

yellow to orange

color

white to beige


Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable



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