QVHLSET
QuicTPD® VHL ligand set
Sustainability features
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About This Item
NACRES:
NA.21
Pricing and availability is not currently available.
packaging
pkg of 50 mg
Quality Segment
sustainability
Sustainability features
storage temp.
2-8°C
General description
(S,R,S)-AHPC and (S,R,S)-AHPC-Me are recruiters of von-Hippel-Lindau (VHL) protein that can be leveraged for targeted protein degradation research. They are provided at 50 mg each.
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Application
Useful for construction of VHL based partial protacs of full protacs, by utilizing the amine terminus to add suitable linkers with peptide coupling reactions. These can also be used as controls/competitors to confirm target engagement of putative protacs.
Features and Benefits
Quantities provided are sufficient to do at least 96 reactions at 1 micromole each with a D2B approach with a library of suitable bifunctional linkers ending in carboxylic acid terminus to generate a library of partial protacs or full protacs.
Other Notes
VHL Ligand Set part of QuicTPD® kit
Legal Information
QuicTPD is a registered trademark of Merck KGaA, Darmstadt, Germany
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| Quality Level 100 | Quality Level 100 | Quality Level 100 | Quality Level 100 |
| storage temp. 2-8°C | storage temp. 2-8°C | storage temp. 2-8°C | storage temp. 2-8°C |
| greener alternative category | greener alternative category | greener alternative category | greener alternative category |
| sustainability Greener Alternative Product | sustainability Greener Alternative Product | sustainability Greener Alternative Product | sustainability Greener Alternative Product |
| packaging pkg of 50 mg | packaging pkg of 50 mg | packaging pkg of 10 mg | packaging - |
Storage Class
11 - Combustible Solids
WGK
WGK 3
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