Ultra pure 1M TRIS-HCL

Our Ultra Pure & DNA-Free 1M Tris-HCl is a premium-grade buffer solution designed for the most demanding molecular applications. Prepared using high-purity Tris base (Tris(hydroxymethyl)aminomethane hydrochloride) in 18 megohm ultra pure water and sterile 0.2 μm filtered, this solution delivers exceptional consistency, reliability, and purity in every lot. Its DNA-free formulation ensures complete confidence in sensitive downstream applications where contamination is simply not an option.

Our Ultra pure & DNA-Free 1M Tris-HCl is a highly versatile reagent with broad applicability across molecular biology and biochemistry workflows, including:
High-Sensitivity Molecular Biology- Methods capable of detecting extremely small amounts of DNA, RNA, or proteins—often down to single molecules.

• Molecular Diagnostics (qPCR, ddPCR, RT-PCR)-

• Eliminates false signals from reagent-derived DNA in pathogen detection, viral load quantification, and rare mutation analysis.
• Single-Cell Genomics- Prevents background DNA interference in workflows like scRNA-seq, ATAC-seq, and single-cell DNA methylation profiling.
• CRISPR-Based Genome Editing- Critical for gRNA production, ribonucleoprotein (RNP) complex assembly, and editing validation assays where DNA contamination risks off-target effects.
• Next-Generation Sequencing (NGS)- Safeguards sequencing library preparation (Illumina, PacBio) and low-input workflows (e.g., metagenomics, ChIP-seq) from reagent-borne DNA artifacts.
• Forensic & Cell-Free Nucleic Acid Analysis- Neutralizes contamination in STR profiling, mitochondrial DNA analysis, and liquid biopsy (ctDNA/exosome RNA) workflows.

PCR, qPCR, RT-PCR, nucleic acid amplification, agarose gel electrophoresis, DNA storage

Why Choose Our Ultra pure & DNA-Free 1M Tris-HCl?
Not all Tris-HCl solutions are created equal. Here is why our customers trust our product for their most critical workflows:

• Uncompromising Purity-

• Prepared using pH-adjusted, high-purity Tris base dissolved in 18 megohm ultrapure water — the gold standard in laboratory-grade water — our solution minimizes the risk of ionic or organic impurities that could interfere with sensitive assays, enzyme activity, or downstream analytical measurements.
• DNA-Free- Contaminating DNA in a buffer solution can compromise nucleic acid-based experiments, leading to false positives and unreliable data. Our product is rigorously tested and certified DNA-free, giving you confidence in every experiment — from routine PCR to high-sensitivity next-generation sequencing (NGS) workflows.
• Sterile 0.2 µm Filtered- Every batch undergoes 0.2 µm sterile filtration, effectively removing particulate matter and microbial contaminants. This ensures the solution remains clean and stable throughout its shelf life and is suitable for use in sterile or semi-sterile laboratory environments.
• Ready-to-Use Convenience- Say goodbye to time-consuming buffer preparation. Our pre-made 1M solution is ready to use straight from the bottle, reducing preparation time, minimizing weighing and dissolution errors, and freeing up valuable bench time for what matters most — your science.
• Broad Versatility- From gel electrophoresis and nucleic acid isolation to immunoprecipitation and general buffer preparation, our 1M Tris-HCl solution is a trusted reagent across a wide spectrum of molecular biology and biochemistry applications — making it a true workhorse in any well-equipped laboratory.
• Consistent, Reproducible Results- Manufactured under strict quality control protocols with thorough lot-to-lot testing, our product delivers the consistency and reproducibility that modern research demands. When your experiments depend on reliable buffers, our Tris-HCl solution delivers every time.