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00541

Ruthenium Red

85.0-115.0% (calc. on dry basis, AT)

Synonym(s):

Ammoniated ruthenium oxychloride

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1 g
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$275.00
5 g

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$926.00

About This Item

Linear Formula:
[(NH3)5RuORu(NH3)4ORu(NH3)5]Cl6
CAS Number:
11103-72-3
Molecular Weight:
786.35
NACRES:
NA.47
PubChem Substance ID:
329747091
UNSPSC Code:
12171500
MDL number:
MFCD00011479
Colour Index Number:
77800

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Quality Level

100

assay

85.0-115.0% (calc. on dry basis, AT)

form

powder

impurities

~5% water

solubility

water: 10 mg/mL, clear to turbid

εmax

≥150 at 529-539 nm

suitability

suitable for microscopy

application(s)

diagnostic assay manufacturing
hematology
histology

storage temp.

room temp

SMILES string

N.N.N.N.N.N.N.N.N.N.N.N.N.N.[Cl-].[Cl-].[Cl-].[Cl-].[Cl-].[Cl-].[Ru++]O[Ru++]O[Ru++]

InChI

1S/6ClH.14H3N.2O.3Ru/h6*1H;14*1H3;;;;;/q;;;;;;;;;;;;;;;;;;;;;;3*+2/p-6

InChI key

ZXYSDUPLHOJIOR-UHFFFAOYSA-H

General description

Ruthenium red is an inorganic cationic dye. It is also known as ammoniated ruthenium oxychloride. It is a large coordination complex consisting of three metal atoms connected by bridging oxygens, in addition to multiple amine ligands.

Application

Inhibits mitochondrial Ca2+ uniporter; capsaicin antagonist; blocks VR1 vanilloid receptor-coupled ion channels.
Ruthenium red is suitable for use in light microscopy to stain pectins. It is also used to stain glycosaminoglycans by employing a two-color staining method with alcian blue. It serves as a typical basic dye at a higher pH that stains nuclei, Nissl substance, cartilage matrix, and mast cell granules. Other applications involving light microscopy include staining resin-embedded material. Ruthenium red is an important component of fixatives of the bacterial glycocalyx.

Biochem/physiol Actions

Ruthenium red inhibits mitochondrial Ca2+ uniporter. It is a known capsaicin antagonist. Additionally, it is known to block VR1 vanilloid receptor-coupled ion channels.

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This Item
R2751557450373567
Ruthenium Red 85.0-115.0% (calc. on dry basis, AT)

Sigma-Aldrich

00541

Ruthenium Red

Ruthenium Red Technical grade

Sigma-Aldrich

R2751

Ruthenium Red

Ruthenium Red A blocker of transmembrane Ca2+ fluxes (IC50 = 7 µM) that attenuates capsaicin-induced cation channel opening.

Sigma-Aldrich

557450

Ruthenium Red

Ruthenium(III) nitrosyl nitrate solution in dilute nitric acid

Sigma-Aldrich

373567

Ruthenium(III) nitrosyl nitrate solution

suitability

suitable for microscopy

suitability

-

suitability

-

suitability

-

form

powder

form

powder

form

solid

form

liquid

solubility

water: 10 mg/mL, clear to turbid

solubility

water: 10 mg/mL

solubility

ammonia: soluble, water: soluble

solubility

-

application(s)

diagnostic assay manufacturing
hematology
histology

application(s)

diagnostic assay manufacturing
hematology
histology

application(s)

-

application(s)

PEM fuel cells
homogeneous catalyst
material synthesis precursor

Quality Level

100

Quality Level

200

Quality Level

100

Quality Level

100

storage temp.

room temp

storage temp.

room temp

storage temp.

10-30°C

storage temp.

-

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pictograms

Exclamation mark
GHS07

signalword

Warning

hcodes

H302

Hazard Classifications

Acute Tox. 4 Oral

Storage Class

13 - Non Combustible Solids

wgk

WGK 3

flash_point_f

No data available

flash_point_c

No data available

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Certificates of Analysis (COA)

Lot/Batch Number
BCCM3255
BCCM5854
BCCJ0685
BCCG9492
BCCF6659

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Global Trade Item Number

SKUGTIN
33412-100MG-R04061826737859
00541-5G04061833328361
00541-1G04061826651629

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