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MilliporeSigma

00541

Ruthenium Red

85.0-115.0% (calc. on dry basis, AT)

Synonym(s):

Ammoniated ruthenium oxychloride

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$463.00

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About This Item

Linear Formula:
[(NH3)5RuORu(NH3)4ORu(NH3)5]Cl6
CAS Number:
11103-72-3
Molecular Weight:
786.35
NACRES:
NA.47
PubChem Substance ID:
329747091
UNSPSC Code:
12171500
MDL number:
MFCD00011479
Colour Index Number:
77800

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SMILES string

N.N.N.N.N.N.N.N.N.N.N.N.N.N.[Cl-].[Cl-].[Cl-].[Cl-].[Cl-].[Cl-].[Ru++]O[Ru++]O[Ru++], N.N.N.N.N.N.N.N.N.N.N.N.N.N.[Cl-].[Cl-].[Cl-].[Cl-].[Cl-].[Cl-].[Ru++]O[Ru++]O[Ru++]

InChI

1S/6ClH.14H3N.2O.3Ru/h6*1H;14*1H3;;;;;/q;;;;;;;;;;;;;;;;;;;;;;3*+2/p-6

InChI key

ZXYSDUPLHOJIOR-UHFFFAOYSA-H

assay

85.0-115.0% (calc. on dry basis, AT)

form

powder

impurities

~5% water

solubility

water: 10 mg/mL, clear to turbid

εmax

≥150 at 529-539 nm

suitability

suitable for microscopy

application(s)

diagnostic assay manufacturing
hematology
histology

storage temp.

room temp

Quality Level

100

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1 of 4

This Item
R2751557450373567
Ruthenium Red 85.0-115.0% (calc. on dry basis, AT)

Sigma-Aldrich

00541

Ruthenium Red

Ruthenium Red Technical grade

Sigma-Aldrich

R2751

Ruthenium Red

Ruthenium Red A blocker of transmembrane Ca2+ fluxes (IC50 = 7 µM) that attenuates capsaicin-induced cation channel opening.

Sigma-Aldrich

557450

Ruthenium Red

Ruthenium(III) nitrosyl nitrate solution in dilute nitric acid

Sigma-Aldrich

373567

Ruthenium(III) nitrosyl nitrate solution

grade

for microscopy

grade

-

grade

-

grade

-

solubility

water: 10 mg/mL, clear to turbid

solubility

water: 10 mg/mL

solubility

ammonia: soluble, water: soluble

solubility

-

form

powder

form

powder

form

solid

form

liquid

application(s)

diagnostic assay manufacturing
hematology
histology

application(s)

diagnostic assay manufacturing
hematology
histology

application(s)

-

application(s)

-

storage temp.

room temp

storage temp.

room temp

storage temp.

10-30°C

storage temp.

-

assay

85.0-115.0% (calc. on dry basis, AT)

assay

34-39% (RUTHENIUM, ICP)

assay

-

assay

-

Application

Inhibits mitochondrial Ca2+ uniporter; capsaicin antagonist; blocks VR1 vanilloid receptor-coupled ion channels.
Ruthenium red is suitable for use in light microscopy to stain pectins. It is also used to stain glycosaminoglycans by employing a two-color staining method with alcian blue. It serves as a typical basic dye at a higher pH that stains nuclei, Nissl substance, cartilage matrix, and mast cell granules. Other applications involving light microscopy include staining resin-embedded material. Ruthenium red is an important component of fixatives of the bacterial glycocalyx.

Biochem/physiol Actions

Ruthenium red inhibits mitochondrial Ca2+ uniporter. It is a known capsaicin antagonist. Additionally, it is known to block VR1 vanilloid receptor-coupled ion channels.

General description

Ruthenium red is an inorganic cationic dye. It is also known as ammoniated ruthenium oxychloride. It is a large coordination complex consisting of three metal atoms connected by bridging oxygens, in addition to multiple amine ligands.

pictograms

Exclamation mark
GHS07

signalword

Warning

hcodes

H302

Hazard Classifications

Acute Tox. 4 Oral

Storage Class

13 - Non Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

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Certificates of Analysis (COA)

Lot/Batch Number
BCCM3255
BCCM5854
BCCJ0685
BCCG9492
BCCF6659

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