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02286

Kollidon® 25

Synonym(s):

Polyvinylpyrrolidone, Polyvinylpyrrolidone K25, PVP, Polyvidone, Povidone

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About This Item

Linear Formula:
(C6H9NO)n
CAS Number:
9003-39-8
NACRES:
NA.25
UNSPSC Code:
12162002
MDL number:
MFCD00149016
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Quality Level

200

impurities

≤1 ppm hydrazine, ≤10 ppm heavy metals (verified on random samples only), ≤10 ppm lead (verified on random samples only), ≤10 ppm vinylpyrrolidinone, ≤3.0% 2-pyrrolidone, ≤400 ppm peroxides (as H2O2), ≤5.0% water, ≤500 ppm aldehydes (as acetaldehyde), ≤5000 ppm formic acid, 12.0-12.8% nitrogen (anhydrous basis)

ign. residue

≤0.1% (verified on random samples only)

pH

3.0-5.0

suitability

complies for Infrared spectrum

application(s)

sample preservation

SMILES string

C=CN1CCCC1=O

InChI

1S/C6H9NO/c1-2-7-5-3-4-6(7)8/h2H,1,3-5H2

InChI key

WHNWPMSKXPGLAX-UHFFFAOYSA-N

Application

The Kollidon products consist of soluble and insoluble grades of polyvinylpyrrolidone (PVP) of various molecular weights and particle sizes. It is used as dry binders, film-formers, stabilizers in suspensions, dispersants for pigments, enzyme stabilisiers and bioavailablility improvers.
Kollidon SR is a blend of polyvinyl acetate and povidone (K 30) in the ratio 8:2 for use as matrix-forming agent. This research grade product is intended for use in R&D and development only.

Other Notes

Polyvinylpyrrolidone is a component of Denhardt′s Solution and is included at a concentration of 1% (w/v) in the standard 50X stock solution.

Legal Information

Kollidon is a registered trademark of BASF SE

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1 of 1

This Item
8142011507061.07302
Kollidon® 25

Sigma-Aldrich

02286

Kollidon® 25

Polyvinylpyrrolidone K 30

Sigma-Aldrich

81420

Polyvinylpyrrolidone

Crospovidone United States Pharmacopeia (USP) Reference Standard

USP

1150706

Crospovidone

Polyvinylpolypyrrolidone Divergan RS

Supelco

1.07302

Polyvinylpolypyrrolidone

suitability

complies for Infrared spectrum

suitability

-

suitability

-

suitability

-

application(s)

sample preservation

application(s)

coatings
pharmaceutical

application(s)

pharmaceutical (small molecule)

application(s)

-

Quality Level

200

Quality Level

200

Quality Level

-

Quality Level

100

impurities

≤1 ppm hydrazine, ≤10 ppm lead (verified on random samples only), ≤3.0% 2-pyrrolidone, ≤5.0% water, ≤5000 ppm formic acid, ≤10 ppm heavy metals (verified on random samples only), ≤400 ppm peroxides (as H2O2), 12.0-12.8% nitrogen (anhydrous basis), ≤10 ppm vinylpyrrolidinone, ≤500 ppm aldehydes (as acetaldehyde)

impurities

-

impurities

-

impurities

-

pH

3.0-5.0

pH

-

pH

-

pH

-

ign. residue

≤0.1% (verified on random samples only)

ign. residue

-

ign. residue

-

ign. residue

-

Storage Class

11 - Combustible Solids

wgk

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable

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Certificates of Analysis (COA)

Lot/Batch Number
BCCK3379
BCCG4333
BCCD9628
BCCC8593
BCCC8592

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Yan-Yan Yin et al.
Inorganic chemistry, 51(8), 4784-4790 (2012-03-31)
Chiral Ni(II) coordination compounds with structures of [NiL(H(2)O)(3)] (1) and {[NiL(H(2)O)]·0.5H(2)O}(n) (2) (H(2)L = thiazolidine 2,4-dicaboxlic acid) have been successfully synthesized by the reaction of Ni(CH(3)COO)(2)·4H(2)O and H(2)L in aqueous solution at 25 and 80 °C, respectively. From the same
Camila Braga Dornelas et al.
Journal of pharmacy & pharmaceutical sciences : a publication of the Canadian Society for Pharmaceutical Sciences, Societe canadienne des sciences pharmaceutiques, 14(1), 17-35 (2011-04-20)
This work describes the preparation of new nanocomposites based on lamellar silicates (AAM-alkyl ammonium montmorillonite) obtained by the intercalation of PVP K30 and glyceril monostearate. By XRD, TGA and DSC analysis the AAM was characterized and its compactation characteristics, functionality
Jianxin Zhang et al.
International journal of pharmaceutics, 414(1-2), 210-217 (2011-06-02)
Nanothermal analysis (NTA) supported by atomic force microscopy imaging has been used to study the changes that occur at the surfaces of solid dispersions of the drug felodipine and the water soluble polymer, polyvinylpyrrolidone (PVP) on exposure to standard pharmaceutical
View All Related Papers

Global Trade Item Number

SKUGTIN
Y000049304061833795408
P3502-100G04061834368021
107069002504022536086392
818887999904022536447544
79330-100G04061832951102
79330-25G04061835176915
P3502-25G04061834368038
P1178-100G04061834354192
818887010004022536447537
02286-500G04061838612328

Questions

1–3 of 3 Questions  

  1. How can I determine the shelf life / expiration / retest date of this product?

    1 answer

    1. If this product has an expiration or retest date, it will be shown on the Certificate of Analysis (COA, CofA). If there is no retest or expiration date listed on the product's COA, we do not have suitable stability data to determine a shelf life. For these products, the only date on the COA will be the release date; a retest, expiration, or use-by-date will not be displayed.
      For all products, we recommend handling per defined conditions as printed in our product literature and website product descriptions. We recommend that products should be routinely inspected by customers to ensure they perform as expected.
      For products without retest or expiration dates, our standard warranty of 1 year from the date of shipment is applicable.
      For more information, please refer to the Product Dating Information document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/418/501/product-dating-information-06-25-mk.pdf

      Helpful?

  2. Good morning, I'm contacting you regarding product 02286, Kollidon 25. I would like to know if Kollidon 25 is the same as Polyvinylpyrrolidone K25 ? thank you for your feedback. Kind regards

    1 answer

    1. Yes, Kollidon 25 is the same as Polyvinylpyrrolidone K25.

      Helpful?

  3. How is shipping temperature determined? And how is it related to the product storage temperature?

    1 answer

    1. Products may be shipped at a different temperature than the recommended long-term storage temperature. If the product quality is sensitive to short-term exposure to conditions other than the recommended long-term storage, it will be shipped on wet or dry-ice. If the product quality is NOT affected by short-term exposure to conditions other than the recommended long-term storage, it will be shipped at ambient temperature. As shipping routes are configured for minimum transit times, shipping at ambient temperature helps control shipping costs for our customers. For more information, please refer to the Storage and Transport Conditions document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/316/622/storage-transport-conditions-mk.pdf

      Helpful?

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