58756
1-(5-Isoquinolinesulfonyl)-3-methylpiperazine
≥98.0% (HPLC)
Synonym(s):
1-(5-Isoquinolinylsulfonyl)-3-methylpiperazine, Iso-H-7
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About This Item
Empirical Formula (Hill Notation):
C14H17N3O2S
CAS Number:
Molecular Weight:
291.37
UNSPSC Code:
12352202
NACRES:
NA.77
PubChem Substance ID:
MDL number:
Beilstein/REAXYS Number:
5445506
Quality Level
assay
≥98.0% (HPLC)
form
powder
storage temp.
2-8°C
SMILES string
CC1CN(CCN1)S(=O)(=O)c2cccc3cnccc23
InChI
1S/C14H17N3O2S/c1-11-10-17(8-7-16-11)20(18,19)14-4-2-3-12-9-15-6-5-13(12)14/h2-6,9,11,16H,7-8,10H2,1H3
InChI key
QGSCXAWTTISKLF-UHFFFAOYSA-N
Biochem/physiol Actions
Less potent inhibitor of protein kinaseC than H-7
Storage Class
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
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Upregulation of vascular endothelial growth factor by angiotensin II in rat heart endothelial cells.
C C Chua et al.
Biochimica et biophysica acta, 1401(2), 187-194 (1998-04-09)
Vascular endothelial growth factor (VEGF) is a potent mitogen for endothelial cells and a vascular permeability factor. In this study we found that the addition of angiotensin II (AII) to rat heart endothelial cells induced VEGF mRNA production. VEGF mRNA
J Duraj et al.
Neoplasma, 44(4), 205-211 (1997-01-01)
The human pre-B acute lymphoblastic leukemia cell line REH6 was utilized for characterization of CD45 glycoprotein by monoclonal antibodies (mAb) recognizing four distinct CD45 antigen specificities, i.e. nonrestricted CD45, restricted CD45RA, CD45RB and CD45R0. Immunoprecipitation revealed two antigen specificities on
C D Balaban et al.
Brain research, 845(1), 97-101 (1999-10-26)
This study tests the hypothesis that activation of protein kinase C (PKC) is a critical step for early recovery from spontaneous nystagmus after unilateral ablation of the vestibular periphery. Halothane-NO(2)-O(2)-anesthetized Long-Evans rats received a 5-microl intracerebroventricular bolus of vehicle (distilled
Global Trade Item Number
| SKU | GTIN |
|---|---|
| 58756-5MG-F | 04061832633572 |