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Anti-Nitric Oxide Synthase, Brain (251-270) antibody produced in rabbit

Name: Anti-Nitric Oxide Synthase, Brain (251-270) antibody produced in rabbit
Brand: SIGMA
Price: 798 CAD

IgG fraction of antiserum, buffered aqueous solution

Synonym(s):

Anti-bNOS

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Size/SKU	Availability	Price
0.2 mL	Please contact Customer Service for Availability	$798.00

About This Item

UNSPSC Code:

12352203

NACRES:

NA.41

MDL number:

MFCD01092427

Conjugate:

unconjugated

Clone:

polyclonal

Application:

ARR, WB

Citations:

$798.00

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Properties

biological source

rabbit

Quality Segment

200

conjugate

unconjugated

antibody form

IgG fraction of antiserum

antibody product type

primary antibodies

clone

polyclonal

form

buffered aqueous solution

mol wt

antigen 150-160 kDa

species reactivity

human, rat

technique(s)

microarray: suitable, western blot: 1:10,000 using rat brain extract

UniProt accession no.

P29475

shipped in

dry ice

storage temp.

−20°C

target post-translational modification

unmodified

Gene Information

human ... NOS1(4842)
rat ... Nos1(24598)

Description

General description

Nitric Oxide Synthase, Brain (NOS1) is mapped to human chromosome 12q24.22. The NOS isoform found in neurons is a 150 kDa protein. It is also termed as brain NOS (bNOS). Human bNOS and endothelial NOS (eNOS) share 52% amino acid identity, and rat and human bNOS share 93% amino acid identity.

Immunogen

synthetic peptide corresponding to nitric oxide synthase (NOS) of rat brain origin (bNOS, amino acids 251-270) conjugated to KLH. The immunogen sequence is highly conserved in human bNOS.

Application

Anti-Nitric Oxide Synthase, Brain (251-270) antibody produced in rabbit has been used in:

double immunolabelling,
immunofluorescence
western blotting

Biochem/physiol Actions

Nitric Oxide Synthase, Brain (bNOS) is present also in skeletal muscle, where it is complexed with dystrophin and is absent in Duchenne muscular dystrophy (DMD). Neuronal and endothelial NOS are constitutively expressed and are dependent on Ca²⁺ calmodulin for nitric oxide (NO) production.

Physical form

Solution in 0.01 M phosphate buffered saline, pH 7.4, containing 15 mM sodium azide.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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This Item	N7280	N2280	N217
$Anti-Nitric Oxide Synthase, Brain (251-270) antibody produced in rabbit IgG fraction of antiserum, buffered aqueous solution$ Sigma-Aldrich N7155 Anti-Nitric Oxide Synthase, Brain (251-270) antibody produced in rabbit	$Anti-Nitric Oxide Synthase, Brain (1409-1429) antibody produced in rabbit IgG fraction of antiserum, buffered aqueous solution$ Sigma-Aldrich N7280 Anti-Nitric Oxide Synthase, Brain (1409-1429) antibody produced in rabbit	Sigma-Aldrich N2280 Monoclonal Anti-Nitric Oxide Synthase, Brain (1-181) antibody produced in mouse	Sigma-Aldrich N217 Anti-Nitric Oxide Synthase, Universal antibody produced in rabbit
conjugate unconjugated	conjugate unconjugated	conjugate unconjugated	conjugate unconjugated
antibody form IgG fraction of antiserum	antibody form IgG fraction of antiserum	antibody form ascites fluid	antibody form affinity isolated antibody
biological source rabbit	biological source rabbit	biological source mouse	biological source rabbit
Quality Level 200	Quality Level 200	Quality Level 200	Quality Level 200
mol wt antigen 150-160 kDa	mol wt antigen 150-160 kDa	mol wt antigen 150-160 kDa	mol wt -
species reactivity human, rat	species reactivity rat	species reactivity rat, goat, pig, human	species reactivity mouse, bovine, rat, human, pig

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Storage Class

10 - Combustible liquids

wgk

WGK 2

flash_point_f

Not applicable

flash_point_c