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Monoclonal Anti-p19^INK4d antibody produced in mouse

Name: Monoclonal Anti-p19<SUP>INK4d</SUP> antibody produced in mouse
Brand: SIGMA

clone DCS-100, ascites fluid

Synonym(s):

Anti-INK4D, Anti-p19, Anti-p19-INK4D

About This Item

UNSPSC Code:

12352203

NACRES:

NA.41

MDL number:

MFCD01324442

Conjugate:

unconjugated

Clone:

DCS-100, monoclonal

Application:

ARR, ICC, IHC (p), IP, WB

Citations:

This product is discontinued. Contact Technical Servicefor assistance.

Properties

biological source

mouse

conjugate

unconjugated

antibody form

ascites fluid

antibody product type

primary antibodies

clone

DCS-100, monoclonal

mol wt

antigen 19 kDa

contains

15 mM sodium azide

species reactivity

human

technique(s)

immunocytochemistry: suitable, immunohistochemistry (formalin-fixed, paraffin-embedded sections): suitable, immunoprecipitation (IP): suitable, microarray: suitable, western blot: 1:1,000 using a cultured human tumor cell line extract

isotype

IgG1

UniProt accession no.

P55273

shipped in

dry ice

storage temp.

−20°C

target post-translational modification

unmodified

Gene Information

human ... CDKN2D(1032)

Description

General description

Cyclin dependent kinase inhibitor 2D (CDKN2D), also referred to as p19INK4d, is part of the inhibitors of cyclin-dependent kinases (INK4) family. It consists of 166 amino acids and five ankyrin-like repeats that aid in protein-protein interactions. The gene encoding this protein is localized on human chromosome 19p13.

Immunogen

recombinant human p19^INK4d.

Application

Monoclonal Anti-p19INK4d antibody produced in mouse has been used in microarray.

Biochem/physiol Actions

Cyclin dependent kinase inhibitor 2D (CDKN2D) functions as a modulator of the cell cycle and has a role in DNA damage response. It acts as a chromatin accessibility factor. The protein associates with cyclin-dependent kinase 4 and 6 and inhibits their kinase activity.

Shows no cross-reactivity with other closely related Cdk inhibitors, such as p15^INK4b, p16^INK4a and p18^INK4c.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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This Item	SAB1402146	C7464	C7089
Sigma-Aldrich P4354 Monoclonal Anti-p19^INK4d antibody produced in mouse	Sigma-Aldrich SAB1402146 Monoclonal Anti-CDKN2D antibody produced in mouse	Sigma-Aldrich C7464 Monoclonal Anti-Cyclin D1 antibody produced in mouse	Sigma-Aldrich C7089 Monoclonal Anti-Cdk7/CAK antibody produced in mouse
clone DCS-100, monoclonal	clone 2E10, monoclonal	clone DCS-6, monoclonal	clone MO-1.1, monoclonal
conjugate unconjugated	conjugate unconjugated	conjugate unconjugated	conjugate unconjugated
antibody form ascites fluid	antibody form purified immunoglobulin	antibody form ascites fluid	antibody form ascites fluid
biological source mouse	biological source mouse	biological source mouse	biological source mouse
Gene Information human ... CDKN2D(1032)	Gene Information human ... CDKN2D(1032)	Gene Information human ... CCND1(595) mouse ... Ccnd1(12443) rat ... Ccnd1(58919)	Gene Information human ... CDK7(1022)
species reactivity human	species reactivity human	species reactivity rat, mouse, human, monkey	species reactivity human

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Storage Class

10 - Combustible liquids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

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Global Trade Item Number

SKU	GTIN
P4354-.2ML	04061837868320

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