Skip to Content
MilliporeSigma

Skip To

A1895

Aurintricarboxylic acid

≥85% purity (titration), practical grade, powder

Synonym(s):

ATA

Sign In to View Organizational & Contract Pricing.

Select a Size

Change View
Pack SizeSKUAvailabilityPrice
5 g
Please contact Customer Service for Availability
$106.00
25 g
Please contact Customer Service for Availability
$364.00

About This Item

Empirical Formula (Hill Notation):
C22H14O9
CAS Number:
Molecular Weight:
422.34
NACRES:
NA.47
PubChem Substance ID:
UNSPSC Code:
12171500
EC Number:
224-628-1
MDL number:

$106.00


Please contact Customer Service for Availability

Request a Bulk Order
Technical Service
Need help? Our team of experienced scientists is here for you.
Let Us Assist


Product Name

Aurintricarboxylic acid, practical grade, ≥85% (titration), powder

grade

practical grade

Quality Level

assay

≥85% (titration)

form

powder

technique(s)

titration: suitable

color

red to very dark red, and Red-Brown andBrown-Red

mp

300 °C (lit.)

solubility

1 M NH4OH: 10 mg/mL

application(s)

diagnostic assay manufacturing
hematology
histology

storage temp.

room temp

SMILES string

OC(=O)c1cc(ccc1O)C(\c2ccc(O)c(c2)C(O)=O)=C3\C=CC(=O)C(=C3)C(O)=O

InChI

1S/C22H14O9/c23-16-4-1-10(7-13(16)20(26)27)19(11-2-5-17(24)14(8-11)21(28)29)12-3-6-18(25)15(9-12)22(30)31/h1-9,23-24H,(H,26,27)(H,28,29)(H,30,31)

InChI key

GIXWDMTZECRIJT-UHFFFAOYSA-N

Application

  • Aurintricarboxylic acid has been used to show its anticryptosporidial activity against Cryptosporidium parvum.
  • It has been used as a test substance to identify inhibitors against coronavirus N7-MTases (guanine-N7-methyltransferase).
  • It has been used as a ribonuclease inhibitor.

Biochem/physiol Actions

Readily polymerizes in aqueous solution, forming a stable free radical that inhibits protein-nucleic acid interactions. It is a potent inhibitor of ribonuclease and topoisomerase II by preventing the binding of the nucleic acid to the enzyme. It stimulates tyrosine phosphorylation processes including the Jak2/STAT5 pathway in NB2 lymphoma cells, ErbB4 in neuroblastoma cells, and MAP kinases, Shc proteins, phosphatidylinositide 3-kinase and phospholipase Cγ in PC12 cells. Inhibits apoptosis. It prevents down-regulation of Ca2+ -impermeable GluR2 receptors and inhibits calpain, a Ca2+ -activated protease that is activated during apoptosis.

Compare Similar Items

View Full Comparison

Show Differences

1 of 1

This Item
A0885A36883189400
technique(s)

titration: suitable

technique(s)

-

technique(s)

titration: suitable

technique(s)

-

grade

practical grade

grade

-

grade

ACS reagent

grade

-

color

red to very dark red, and Red-Brown andBrown-Red

color

dark red

color

dark red

color

red

form

powder

form

powder

form

powder or crystals

form

solid

application(s)

diagnostic assay manufacturing
hematology
histology

application(s)

diagnostic assay manufacturing
hematology
histology

application(s)

diagnostic assay manufacturing
hematology
histology

application(s)

-

solubility

1 M NH4OH: 10 mg/mL

solubility

water: soluble 100 mg/mL, dark red

solubility

water: soluble 100 mg/mL

solubility

0.1 M NaOH: 35 mg/mL


Still not finding the right product?

Explore all of our products under Aurintricarboxylic acid


Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Gloves



Choose from one of the most recent versions:

Certificates of Analysis (COA)

Lot/Batch Number

Don't see the Right Version?

If you require a particular version, you can look up a specific certificate by the Lot or Batch number.

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library


Related Content

Product Information Sheet


In vitro and in vivo activity of aurintricarboxylic acid preparations against Cryptosporidium parvum.
Klein P, et al.
The Journal of Antimicrobial Chemotherapy, 62, 1101-1104 (2008)
Red Light-Independent Instability of Oat Phytochrome mRNA in Vivo.
Seeley KA, et al.
Plant Cell, 4, 29-38 (1992)
Yeast-based assays for the high-throughput screening of inhibitors of coronavirus RNA cap guanine-N7-methyltransferase.
Sun Y, et al.
Antiviral Research, 104, 156-164 (2014)



Global Trade Item Number

SKUGTIN
A1895-25G04061833343142
A1895-5G04061833343159

Questions

Reviews

No rating value

Active Filters