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A271

Anti-α2A Adrenergic Receptor antibody produced in rabbit

affinity isolated antibody, buffered aqueous solution

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UNSPSC Code:
12352203
NACRES:
NA.41
MDL number:
Conjugate:
unconjugated
Clone:
polyclonal
Application:
IHC (p), WB
Citations:
6


biological source

rabbit

Quality Segment

conjugate

unconjugated

antibody form

affinity isolated antibody

antibody product type

primary antibodies

clone

polyclonal

form

buffered aqueous solution

mol wt

antigen ~45 kDa

species reactivity

rat, human, mouse, pig

technique(s)

immunohistochemistry (formalin-fixed, paraffin-embedded sections): 1:1000, western blot: 1:500

UniProt accession no.

shipped in

dry ice

storage temp.

−20°C

target post-translational modification

unmodified

Gene Information

human ... ADRA2A(150)
mouse ... Adra2a(11551)
rat ... Adra2a(25083)

General description

Adrenergic receptors (ARs) belong to the 7-transmembrane domain G protein-coupled receptor superfamily that binds to the endogenous catecholamines, epinephrine and norepinephrine. α2AR subtypes block adenylyl cyclase, suppress voltage-sensitive Ca2+ channels, and stimulate receptor dependent K+ channels. All of the α2AR subtypes inhibit adenylyl cyclase through coupling to members of the Gi/Go class of G proteins. They are an important component of the neural circuitry and modulate cardiovascular physiology. The physiological function of the α2ARs in the kidney is to regulate Na+/H+ exchange.
Anti-α2A adrenergic receptor detects rat and mouse α2A adrenergic receptors by immunoblotting and immunohistochemistry. In immunoblotting, the antibody detects an approx. 45kDa band representing α2A receptors in tissues expressing this receptor subtype, although some non-specific bands have also been observed in certain cases.

Immunogen

synthetic peptide derived from amino acids 218-235 of human, mouse, rat, and pig α2A adrenergic receptor. The immunogen sequence is found within the third intracellular loop of the α2A adrenergic receptor subtype.

Application

Rabbit anti-α2A adrenergic receptor antibody can be used for western blot (1:500) and immunohistochemistry (1:1000) applications.

Physical form

Solution in phosphate buffered saline, containing 1 mg/ml BSA and 0.05% sodium azide.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Este artículo
SAB5201000SAB5201012SAB5200997
conjugate

unconjugated

conjugate

Atto 594 conjugate

conjugate

phycoerythrin (R-PE) conjugate

conjugate

Atto 390 conjugate

antibody form

affinity isolated antibody

antibody form

purified immunoglobulin

antibody form

purified immunoglobulin

antibody form

purified immunoglobulin

Quality Level

200

Quality Level

100

Quality Level

100

Quality Level

100

biological source

rabbit

biological source

mouse

biological source

mouse

biological source

mouse

technique(s)

immunohistochemistry (formalin-fixed, paraffin-embedded sections): 1:1000, western blot: 1:500

technique(s)

immunocytochemistry: suitable, western blot: suitable

technique(s)

immunocytochemistry: suitable, western blot: suitable

technique(s)

immunocytochemistry: suitable, western blot: suitable

mol wt

antigen ~45 kDa

mol wt

antigen predicted mol wt 50 kDa

mol wt

antigen predicted mol wt 50 kDa

mol wt

antigen predicted mol wt 50 kDa


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Clase de almacenamiento

10 - Combustible liquids

wgk

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, multi-purpose combination respirator cartridge (US)



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