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A4086

Anti-ATF-2 (SS-16) antibody produced in rabbit

affinity isolated antibody, buffered aqueous solution

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About This Item

UNSPSC Code:
12352203
NACRES:
NA.41
MDL number:
Conjugate:
unconjugated
Clone:
polyclonal
Application:
ARR, IP, WB CL
Citations:
5


biological source

rabbit

Quality Level

conjugate

unconjugated

antibody form

affinity isolated antibody

antibody product type

primary antibodies

clone

polyclonal

form

buffered aqueous solution

mol wt

antigen 65 kDa

species reactivity

human

technique(s)

immunoprecipitation (IP): 5 μg using lysates of human K562 cells, microarray: suitable, western blot (chemiluminescent): 1:250 using whole cell extract of human K562 or Jurkat cells

UniProt accession no.

shipped in

dry ice

storage temp.

−20°C

target post-translational modification

unmodified

Gene Information

human ... ATF2(1386)

General description

ATF2 (Activating Transcription Factor 2, CRE-BP,HB-16, CREB2, TREB-7) belongs to the ATF/CREB family of basic region leucine zipper DNAbinding proteins. ATF2 regulates transcription by binding to a consensus cAMP response element (CRE) in the promoter of various viral and cellular genes. Rabbit anti-ATF-2 (SS-16) antibody recognizes human ATF2 by immunoblotting (65kDa) and immunoprecipitation. Staining of ATF2 by immunoblotting is inhibited by the immunizing peptide.

Immunogen

synthetic peptide corresponding to amino acids 490-505 of human ATF-2.

Application

Rabbit anti-ATF-2 can be used for immunoprecipitation (5μg, using lysates of human K562 cells), microarray, and chemiluminescent western blot (1:250, using whole cell extract of human K562 or Jurkat cells).

Physical form

Solution in 0.01 M phosphate buffered saline, pH 7.4, containing 1% BSA and 15 mM sodium azide.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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This Item
SAB4500449SAB5700288SAB4500448
biological source

rabbit

biological source

rabbit

biological source

rabbit

biological source

rabbit

antibody form

affinity isolated antibody

antibody form

affinity isolated antibody

antibody form

affinity isolated antibody

antibody form

affinity isolated antibody

conjugate

unconjugated

conjugate

unconjugated

conjugate

-

conjugate

unconjugated

Quality Level

200

Quality Level

-

Quality Level

100

Quality Level

-

UniProt accession no.

P15336

UniProt accession no.

P15336

UniProt accession no.

P15336

UniProt accession no.

P15336

shipped in

dry ice

shipped in

wet ice

shipped in

wet ice

shipped in

wet ice


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Storage Class

12 - Non Combustible Liquids

wgk

nwg

flash_point_f

Not applicable

flash_point_c

Not applicable



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F Liu et al.
Cell, 61(7), 1217-1224 (1990-06-29)
The adenovirus E1a protein stimulates transcription of viral early genes. Recent experiments indicate that E1a contains a transcriptional activating region, which functions when directed to a promoter. Because E1a is not a sequence-specific DNA binding protein, how it targets to
F Liu et al.
Nature, 368(6471), 520-525 (1994-04-07)
A puzzling property of the transcriptional activators encoded by several animal viruses is their ability to function promiscuously. The adenovirus E1a protein, for example, stimulates transcription of adenoviral genes as well as a wide variety of other viral and cellular
X Y Li et al.
Genes & development, 10(5), 517-527 (1996-03-01)
ATF-2 is a cellular basic region-leucine zipper (bZIP) transcription factor that can mediate diverse transcriptional responses, including activation by the adenovirus Ela protein. ATF-2 contains an activation domain, required for transcriptional activity, but in the absence of an appropriate inducer



Global Trade Item Number

SKUGTIN
A4086-.2ML04061837768163

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