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A6284

Human IgG−Agarose

suspension

Synonym(s):

IgG Agarose

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5 mL

Available to ship TODAYfromMILWAUKEE

$367.00

About This Item

UNSPSC Code:
12352203
NACRES:
NA.46
MDL number:
Conjugate:
agarose conjugate
Species reactivity:
-
Application:
Citations:
14

$367.00


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conjugate

agarose conjugate

Quality Level

form

suspension

extent of labeling

≥5 mg per mL

matrix

Cross-linked 4% beaded agarose

matrix activation

cyanogen bromide

matrix spacer

1 atom

storage temp.

2-8°C

General description

Human IgGs are glycoprotein antibodies that contain two equivalent light chains and a pair of identical heavy chains. IgGs have four distinct isoforms, ranging from IgG1 to IgG4. These antibodies regulate immunological responses to allergy and pathogenic infections. IgGs have also been implicated in complement fixation and autoimmune disorders[1][2].

Application

IgG-Agarose is an immuno-adsorbent that can be used to affinity purify antibodies, remove species-specific cross-reacting antibodies or remove contaminating antibodies from an antiserum preparation. Typically, cross-reacting antibodies may be removed from an antiserum preparation using an equal volume of IgG-Agarose (resin volume). However, the resin to antiserum ratio will vary with individual applications.
Tandem affnitiy purification pulldown was performed in yeast cultures using agarose-linked human IgG. Supernatants were mixed with 30μl of agarose beads overnight. [3]

Physical form

Suspension in 0.5 M NaCl containing preservative.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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A3316A2909A3187
conjugate

agarose conjugate

conjugate

agarose conjugate

conjugate

agarose conjugate

conjugate

alkaline phosphatase conjugate

storage temp.

2-8°C

storage temp.

2-8°C

storage temp.

2-8°C

storage temp.

2-8°C

form

suspension

form

PBS suspension

form

saline suspension

form

buffered aqueous glycerol solution

matrix activation

cyanogen bromide

matrix activation

-

matrix activation

cyanogen bromide

matrix activation

-

extent of labeling

≥5 mg per mL

extent of labeling

-

extent of labeling

≥5 mg per mL

extent of labeling

-

Quality Level

200

Quality Level

200

Quality Level

200

Quality Level

200


Storage Class

10 - Combustible liquids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable



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Graciela C Calabrese et al.
Thrombosis research, 113(3-4), 243-250 (2004-05-14)
Dermatan sulfate (DS) is a member of the family of structurally complex, sulfated, linear heteropolysaccharides called glycosaminoglycans (GAGs). It has a similar structure to heparin and heparan sulfate (HS), but with acetylgalactosamine replacing glucosamine, and the uronic acid moiety, mainly
Pierre Fotso et al.
The Journal of biological chemistry, 280(30), 27613-27623 (2005-06-04)
The conserved oligomeric Golgi (COG) complex is an evolutionarily conserved peripheral membrane oligomeric protein complex that is involved in intra-Golgi protein trafficking. The COG complex is composed of eight subunits that are located in two lobes; Lobe A contains COG1-4
Graciela C Calabrese et al.
Thrombosis research, 105(6), 537-541 (2002-07-02)
Antithrombin (AT) high affinity of unfractionated heparin (UFH) resides in a specific pentasaccharide sequence. Heparin also regulates complement activity on the classical and the alternative pathways. Most experimental pieces of evidence accumulated show that these important activities reside in different



Global Trade Item Number

SKUGTIN
A6284-5ML04061838160799
A6284-2ML04061838236227

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