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A7549

抗アポトーシス誘導因子抗体 ウサギ宿主抗体

IgG fraction of antiserum, buffered aqueous solution

別名:

抗AIF抗体

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この商品について

UNSPSC Code:
12352203
NACRES:
NA.41
MDL number:
MFCD02685955
Conjugate:
unconjugated
Clone:
polyclonal
Application:
ARR, WB
Citations:
12

biological source

rabbit

conjugate

unconjugated

antibody form

IgG fraction of antiserum

antibody product type

primary antibodies

clone

polyclonal

form

buffered aqueous solution

mol wt

antigen 57 kDa

species reactivity

mouse, human

packaging

antibody small pack of 25 μL

technique(s)

microarray: suitable, western blot: 1:1,000 using human epitheloid carcinoma HeLa cell extract and mouse brain extract

UniProt accession no.

O95831

shipped in

dry ice

storage temp.

−20°C

target post-translational modification

unmodified

Gene Information

human ... AIFM1(9131)
mouse ... Aifm1(26926)

General description

Apoptosis-Inducing Factor (AIF) is a mitochondrial flavoprotein that can induce apoptosis in isolated nuclei. Studies have reported that AIF can induce the realease of cytochrome c and caspase 9. Bcl-2 is known to inhibit AIF release without affecting its apoptotic functions.
Rabbit Anti-AIF antibody recognizes human and mouse AIF (57kDa). Staining of AIF in immunoblotting is specifically inhibited with the AIF immunizing peptide (human, amino acids 593-613).
Apoptosis-inducing factor (AIF) is encoded by the gene mapped to human chromosome X (Xq25-Xq26). It is a 57 kDa mitochondrial flavoprotein. AIF contains two mitochondrial localization sequences and two putative nuclear localization sequences.

Immunogen

ヒトアポト-シス誘導因子(AIF)のC末端アミノ酸593-613に相当する合成ペプチドのKLH結合体。

Application

Protein lysates from 2CLL, 10 MCl and Jeko-1 cells were analyzed by western blot using anti-AIF as the primary antibody. Cells also underwent intracellular delivery by being transfected with anti-AIF at a final dilution of 1:2500 and then analyzed by FLOW cytometry.
Rabbit Anti-Apoptosis-Inducing Factor (AIF) antibody has been used for immunoblot analysis at 1:1000 and 1:2000 dilutions. The antibody can also be used for microarray applications.

Biochem/physiol Actions

Microinjection of apoptosis-inducing factor (AIF) into the cytoplasm of intact cells induces chromatin condensation, dissipation of the mitochondrial transmembrane potential and exposure of phosphatidylserine in the plasma membrane.

Physical form

0.01M PBS溶液 (pH 7.4, 15mMアジ化ナトリウム含有)。

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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当該品目
AB16501SAB5700185P0357
抗アポトーシス誘導因子抗体 ウサギ宿主抗体 IgG fraction of antiserum, buffered aqueous solution

Sigma-Aldrich

A7549

抗アポトーシス誘導因子抗体 ウサギ宿主抗体

Anti-AIF Antibody, internal domain Chemicon®, from rabbit

Sigma-Aldrich

AB16501

Anti-AIF Antibody, internal domain

Anti-AIF antibody produced in rabbit

Sigma-Aldrich

SAB5700185

Anti-AIF antibody produced in rabbit

抗p57Kip2 ウサギ宿主抗体 IgG fraction of antiserum, buffered aqueous solution

Sigma-Aldrich

P0357

抗p57Kip2 ウサギ宿主抗体

description

IgG fraction of antiserum, buffered aqueous solution

description

Chemicon®, from rabbit

description

-

description

IgG fraction of antiserum, buffered aqueous solution

antibody form

IgG fraction of antiserum

antibody form

purified immunoglobulin

antibody form

affinity isolated antibody

antibody form

IgG fraction of antiserum

biological source

rabbit

biological source

rabbit

biological source

rabbit

biological source

rabbit

conjugate

unconjugated

conjugate

unconjugated

conjugate

unconjugated

conjugate

unconjugated

UniProt accession no.

O95831

UniProt accession no.

O95831

UniProt accession no.

O95831

UniProt accession no.

P49918

mol wt

antigen 57 kDa

mol wt

-

mol wt

26, 28, 35, 66

mol wt

antigen 57 kDa

Gene Information

human ... AIFM1(9131)
mouse ... Aifm1(26926)

Gene Information

human ... AIFM1(9131)

Gene Information

human ... AIFM1(9131)

Gene Information

human ... CDKN1C(1028)
mouse ... Cdkn1c(12577)

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保管分類

12 - Non Combustible Liquids

wgk

WGK 2

flash_point_f

Not applicable

flash_point_c

Not applicable

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