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MilliporeSigma

A8728

Anti-phospho-β-Arrestin (pSer412) antibody produced in rabbit

affinity isolated antibody, aqueous solution

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About This Item

UNSPSC Code:
12352203
NACRES:
NA.41
MDL number:
Conjugate:
unconjugated
Clone:
polyclonal
Application:
WB
Citations:
-
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biological source

rabbit

Quality Level

conjugate

unconjugated

antibody form

affinity isolated antibody

antibody product type

primary antibodies

clone

polyclonal

form

aqueous solution

species reactivity

rat, mouse

technique(s)

western blot: suitable

UniProt accession no.

shipped in

dry ice

storage temp.

−70°C

target post-translational modification

phosphorylation (pSer412)

Gene Information

mouse ... Arrb2(216869)
rat ... LOC288930(288930)

General description

β-arrestin-1 is a scaffold protein that is highly expressed in the central nervous system. This adaptor protein regulates mitogenic signaling, and also mediates the desentization and internalization of G protein coupled receptors (GPCRs).
Rabbit Anti-phospho-β-Arrestin (pSer412) antibody detects mouse and rat β-arrestin-1. The antibody is also expected to react with human and cow antigens due to the high degree of homology (77%).

Immunogen

synthetic phosphopeptide derived from the region of rat β-arrestin-1 that contains serine 412.

Application

Rabbit Anti-phospho-beta-Arrestin (pSer412) antibody can be used for western blot assays.

Physical form

Solution in Dulbecco′s PBS, pH 7.3 with 1 mg/mL BSA and 0.05% Sodium azide.


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Storage Class

10 - Combustible liquids



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Global Trade Item Number

SKUGTIN
A8728-1VL04061823098496