B2017

Boc-Ala-Pro-Nva p-chlorothiobenzyl ester

Name: Boc-Ala-Pro-Nva p-chlorothiobenzyl ester
Brand: SIGMA

≥98% (TLC), powder

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About This Item

Empirical Formula (Hill Notation):

C₂₅H₃₆ClN₃O₅S

CAS Number:

90171-50-9

Molecular Weight:

526.09

UNSPSC Code:

12352204

PubChem Substance ID:

24891625

NACRES:

NA.32

MDL number:

MFCD00063386

Key Documents

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Product Name

Boc-Ala-Pro-Nva p-chlorothiobenzyl ester,

SMILES string

CCCC(NC(=O)C1CCCN1C(=O)C(C)NC(=O)OC(C)(C)C)C(=O)SCc2ccc(Cl)cc2

InChI

1S/C25H36ClN3O5S/c1-6-8-19(23(32)35-15-17-10-12-18(26)13-11-17)28-21(30)20-9-7-14-29(20)22(31)16(2)27-24(33)34-25(3,4)5/h10-13,16,19-20H,6-9,14-15H2,1-5H3,(H,27,33)(H,28,30)

InChI key

ILVSMEXNXGFDPM-UHFFFAOYSA-N

assay

≥98% (TLC)

form

powder

solubility

chloroform: 10 mg/mL, clear, colorless

storage temp.

−20°C

Quality Level

200

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This Item	M9771	T2803	M0883
Sigma-Aldrich B2017 Boc-Ala-Pro-Nva p-chlorothiobenzyl ester	Sigma-Aldrich M9771 N-Methoxysuccinyl-Ala-Ala-Pro-Val-7-amido-4-methylcoumarin	Sigma-Aldrich T2803 7-Ethoxy-4-(trifluoromethyl)coumarin	Sigma-Aldrich M0883 4-Methylumbelliferyl acetate
assay ≥98% (TLC)	assay ≥98% (HPLC)	assay ≥98% (TLC)	assay ≥98% (TLC)
solubility chloroform: 10 mg/mL, clear, colorless	solubility chloroform: 50 mg/mL, clear, colorless	solubility chloroform: 100 mg/mL, clear, colorless (Soluble in chloroform, methanol, and DMSO.)	solubility chloroform: 100 mg/mL, clear, colorless
Quality Level 200	Quality Level 200	Quality Level 100	Quality Level 100
form powder	form powder	form powder	form powder
storage temp. −20°C	storage temp. −20°C	storage temp. −20°C	storage temp. −20°C

General description

Leucocyte elastase substrate

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

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Active site mapping of the serine proteases human leukocyte elastase, cathepsin G, porcine pancreatic elastase, rat mast cell proteases I and II. Bovine chymotrypsin A alpha, and Staphylococcus aureus protease V-8 using tripeptide thiobenzyl ester substrates.

J W Harper et al.

Biochemistry, 23(13), 2995-3002 (1984-06-19)

The primary subsite specificities of human leukocyte elastase, cathepsin G, porcine pancreatic elastase, rat mast cell proteases I and II, bovine chymotrypsin A alpha, and the protease from strain V-8 of Staphylococcus aureus have been mapped with a series of

Articles

Elastase Function and Importance

Elastase application index for understanding leukocyte elastase, a 29KDa serine endoprotease.

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