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C002

(±)-Quinuclidinyl benzilate

powder

Synonym(s):

(±)-QNB, (±)-Quinuclidinyl α-hydroxydiphenylacetate

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5 mg

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$117.00
$99.45
10 mg
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$205.00
50 mg

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$712.00
$605.20

About This Item

Empirical Formula (Hill Notation):
C21H23NO3
CAS Number:
6581-06-2
Molecular Weight:
337.41
NACRES:
NA.77
PubChem Substance ID:
329774757
UNSPSC Code:
12352200
MDL number:
MFCD00055094
Form:
powder
Quality level:
100

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form

powder

Quality Level

100

color

white

solubility

chloroform: soluble (but decomposes within 24 hrs), methanol: stable (for up to two weeks at -20°C.)

εmax

13,500 at 207.4 nm in methanol

storage temp.

2-8°C

SMILES string

OC(C(=O)OC1CN2CCC1CC2)(c3ccccc3)c4ccccc4

InChI

1S/C21H23NO3/c23-20(25-19-15-22-13-11-16(19)12-14-22)21(24,17-7-3-1-4-8-17)18-9-5-2-6-10-18/h1-10,16,19,24H,11-15H2

InChI key

HGMITUYOCPPQLE-UHFFFAOYSA-N

Biochem/physiol Actions

Nonselective muscarinic acetylcholine receptor antagonist.

Features and Benefits

This compound is a featured product for Neuroscience research. Click here to discover more featured Neuroscience products. Learn more about bioactive small molecules for other areas of research at sigma.com/discover-bsm.
This compound is featured on the Acetylcholine Receptors (Muscarinic) page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

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This Item
A0781SML1861C2020
(±)-Quinuclidinyl benzilate powder

Sigma-Aldrich

C002

(±)-Quinuclidinyl benzilate

Aphidicolin from Nigrospora sphaerica ≥98% (HPLC), powder

Sigma-Aldrich

A0781

Aphidicolin from Nigrospora sphaerica

J104129 fumarate ≥98% (HPLC)

Sigma-Aldrich

SML1861

J104129 fumarate

α-Cyano-4-hydroxycinnamic acid ≥98% (TLC), powder

Sigma-Aldrich

C2020

α-Cyano-4-hydroxycinnamic acid

form

powder

form

powder

form

powder

form

powder

Quality Level

100

Quality Level

300

Quality Level

100

Quality Level

300

storage temp.

2-8°C

storage temp.

2-8°C

storage temp.

2-8°C

storage temp.

2-8°C

solubility

chloroform: soluble (but decomposes within 24 hrs), methanol: stable (for up to two weeks at -20°C.)

solubility

ethanol: 1 mg/mL (stable at least a week at 4°C.), DMSO: 10 mg/mL (stable at least six weeks at −20°C.), methanol: 10 mg/mL, H2O: insoluble

solubility

DMSO: 20 mg/mL, clear

solubility

H2O: slightly soluble, methanol: water: soluble, polar organic solvents: soluble

color

white

color

white

color

white to beige

color

yellow

εmax

13,500 at 207.4 nm in methanol

εmax

-

εmax

-

εmax

-

pictograms

Skull and crossbones
GHS06

signalword

Danger

hcodes

H300

Hazard Classifications

Acute Tox. 2 Oral

Storage Class

6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Faceshields, Gloves

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Certificates of Analysis (COA)

Lot/Batch Number
021M4621V
073K4608

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Monica Salani et al.
Journal of neurochemistry, 108(3), 821-834 (2009-02-04)
Neurotransmitters are considered part of the signaling system active in nervous system development and we have previously reported that acetylcholine (ACh) is capable of enhancing neuronal differentiation in cultures of sensory neurons and N18TG2 neuroblastoma cells. To study the mechanism
M A Siddiqui et al.
Toxicology in vitro : an international journal published in association with BIBRA, 22(7), 1681-1688 (2008-08-02)
Effect of 4-hydroxynonenal (HNE), a long-chain alpha, beta unsaturated aldehyde product, generated by the oxidation of omega-6 polyunsaturated fatty acids on the sensitivity of selected neurotransmitter receptors was studied in PC-12 cells. Cytotoxicity profiling was carried out at varying concentrations
Diego Muñoz-Torrero et al.
Neuro-degenerative diseases, 10(1-4), 96-99 (2012-01-13)
Multifactorial diseases such as Alzheimer's disease (AD) should be more efficiently tackled by drugs which hit multiple biological targets involved in their pathogenesis. We have recently developed a new family of huprine-tacrine heterodimers, rationally designed to hit multiple targets involved
View All Related Papers

Global Trade Item Number

SKUGTIN
C002-50MG04061832081281
C002-10MG04061832081274
C002-5MG04061832081298

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